Cefodroxil monohydrate is formed by a processing which includes a) bringing an aqueous solution of cefadroxil monohydrate to a pH of between 7 to 9 with a suitable titrant; b) lowering the pH to a value of between 5 and 6.5 to obtain a suspension of cefadroxil monohydrate in crystal form; and c) isolating the cefadroxil monohydrate in crystal form from the suspension obtained in step b). The cefadroxil monohydrate thereby obtained exhibits a CIE b value of below 6 and advantageously a CIE b valu...

Cefodroxil monohydrate is formed by a processing which includes a) bringing an aqueous solution of cefadroxil monohydrate to a pH of between 7 to 9 with a suitable titrant

PURPOSE: Complex antibioitics for preventing and treating infection due to drug resistant strains containing existing cepha antibiotics and a beta-lactamase inhibitor are provided to reduce resistance rate and to ensure remarkable antibacterial activity. CONSTITUTION: Complex antibiotics for preventing and treating infection due to drug resistant strains contains existing cepha antibiotics which are selected from the group consisting of first generation second generation fourth generation and fi...

The present invention relates to a process for the preparation of cefadroxil in crystal form comprising a) adding an aqueous solution of cefadroxil to a crystallization vessel and a titrant to keep a pH in the crystallization vessel of between 7 to 9; and b) lowering the pH in the crystallization vessel to a value of between 5 and 6.5 to obtain a suspension of the &bgr;-lactam compound in crystal form. The invention further relates to cefadroxil in crystal form obtainable by the process accordin...

This invention discloses optimized pharmaceutical formulation for bilayer tablet form comprising at least one antibiotic or a pharmaceutically acceptable salt thereof and at least one dissolution enhancing agent sufficient to substantially dissolve said one aqueous diluent binder disintigrants Film forming agents moisture barrier agents. Both ingredient in a single dosages form at same time with high solubility and stability by over coming cross interaction or chemical incompatibilities between ...