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[药品] 包含 'Moxifloxacin '
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公开号
公开日
申请号
申请日
1.
EP2521547A4
2014/3/26
EP20110732210
2011/1/7
专利标题
:Methods and compositions for applying moxifloxacin to the ear
专利权人
:
Regents Of The University Of Minnesota
;
2.
US8680276B2
2014/3/25
US13/056458
2010/3/4
专利标题
:Synthesis of (4as,7as)-octahydro-1h-pyrrolo[3,4-b]pyridine
专利权人
:
The present invention relates to the stereoselective synthesis of (4aS7aS)-octahydro-1H-pyrrolo[34-b]pyridine as well as the conversion thereof to give Moxifloxacin. Particularly the present invention relates to a method for the synthesis of (4aS7aS)-octahydro-1H-pyrrolo[34-b]pyridine of formula (I) comprising: (a) the optical resolution by enzymatic hydrolysis of the intermediate dialkyl-1-alkylcarbonylpiperidine-23-dicarboxylate racemate of formula (II) to give following isolation the intermed...
3.
US8673902B2
2014/3/18
US12/611510
2009/11/3
专利标题
:Method of treating otic infections with moxifloxacin compositions
专利权人
:
Alcon Pharmaceuticals, Ltd.
;
Ophthalmic otic and nasal compositions containing a new class of antibiotics (e.g. moxifloxacin) are disclosed. The compositions preferably also contain one or more anti-inflammatory agents. The compositions may be utilized to treat ophthalmic otic and nasal conditions by topically applying the compositions to the affected tissues.
4.
CN103626768A
2014/3/12
CN20131681344
2013/12/13
专利标题
:Moxifloxacin hydrochloride new preparation process
专利权人
:
5.
US2014066626A1
2014/3/6
US201213977526
2012/9/20
专利标题
:ASYMMETRIC SYNTHESIS METHOD, RELATED RAW MATERIAL AND PREPARATION METHOD OF (S,S)-2,8-DIAZABICYCLO[4,3,0]NONANE
专利权人
:
SHANGHAI PUYI CHEMICAL TECHNOLOGY CO LTD [CN]
;
SHANGHAI PUYI CHEMICAL TECHNOLOGY CO LTD [CN]
;
The present invention relates to an asymmetric synthesis method of a chiral intermediate (S,S)-2,8-diazabicyclo[4,3,0]nonane (I) of moxifloxacin, wherein an imide or enamine compound is obtained by dehydration reaction of the pyrrolidine-3-ketone as shown in formula (II) and chiral amine(R)-1-phenylethylamine, followed by the reduction of the imide or enamine compound to obtain a compound of formula (III) or (IV) having the chiral structure of formula (I), and then a compound of formula (I) is o...
6.
US20140066626A1
2014/3/6
US13/977526
2012/9/20
专利标题
:Asymmetric synthesis method, related raw material and preparation method of (s,s)-2,8-diazabicyclo[4,3,0]nonane
专利权人
:
Shanghai Puyi Chemical Technology Co. Ltd
;
The present invention relates to an asymmetric synthesis method of a chiral intermediate (SS)-28-diazabicyclo[430]nonane (I) of moxifloxacin wherein an imide or enamine compound is obtained by dehydration reaction of the pyrrolidine-3-ketone as shown in formula (II) and chiral amine(R)-1-phenylethylamine followed by the reduction of the imide or enamine compound to obtain a compound of formula (III) or (IV) having the chiral structure of formula (I) and then a compound of formula (I) is obtained...
7.
EP2364141B1
2014/3/5
EP20090765042
2009/12/4
专利标题
:Compacted moxifloxacin
专利权人
:
RATIOPHARM GMBH
;
8.
US8664398B2
2014/3/4
US13/543896
2012/7/9
专利标题
:Moxifloxacin hydrochloride compounds and intermediates and methods for making same
专利权人
:
F.i.s. - Fabbrica Italiana Sintetici S.p.a.
;
Methods for producing moxifloxacin hydrochloride compounds having very low levels of impurities are provided. Compounds produced using such methods and pharmaceutical compositions including such compounds are also provided.
9.
HU229571B1
2014/2/28
HU20020003619
2000/7/25
专利标题
:Aqueous compositions containing moxifloxacin and common salt and process for its preparation
专利权人
:
Bayer Intellectual Property Gmbh
;
10.
US20140051670A1
2014/2/20
US14/062957
2013/10/25
专利标题
:Compositions containing moxifloxacin for treating otic infections
专利权人
:
Alcon, Inc.
;
Ophthalmic otic and nasal compositions containing a new class of antibiotics (e.g. moxifloxacin) are disclosed. The compositions preferably also contain one or more anti-inflammatory agents. The compositions may be utilized to treat ophthalmic otic and nasal conditions by topically applying the compositions to the affected tissues.
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