598890 Disclosed herein are compounds of formula (I) U1-M-U2 wherein the variables are defined in the specification the use of said compounds in the treatment of cancer specifically by sensitising a cell to an apoptotic signal. Additionally said compounds may be used for sequential or concomitant use with a pharmaceutical compound which induces an apoptotic signal such as cytarabine fludarabine 5-fluoro-2'-deoxyuridine 5 gemcitabine methotrexate bleomycin cisplatin cyclophosphamide adriamycin (d...

The invention provides pharmaceutical compositions and method for inhibiting growth of prostatic adenocarcinoma stomach cancer breast cancer endometrial ovarian or other cancers of epithelial secretion or benign prostate hyperplasia (BPH). In one embodiment the pharmaceutical composition includes human rHuPSP94 antigenic portions thereof and functionally equivalent polypeptides thereof. In another embodiment the pharmaceutical composition includes a mixture of human rHuPSP94 antigenic portions t...

The disclosure relates to compounds and compositions for bone formation fracture treatment bone grafting bone fusion cartilage maintenance and repair and methods related thereto. In certain embodiments the disclosure relates to compositions comprising one or more compound(s) disclosed herein such as clotrimazole honokiol magnolol tacrolimus pimecrolimus sirolimus everolimus temsirolimus spironolactone fluticasone fluticasone propionate fluticasone furoate linezolid telmisartan chlorambucil retin...

PROBLEM TO BE SOLVED: To provide a method for treating cervical cancer or cells infected with human papilloma virus. SOLUTION: Interleukin-20 (IL-20) can be administered alone or in conjunction with radiation or chemotherapeutic agents or surgical excision of the involved cells or lesions. The chemotherapeutic agent is selected from the group consisting of bleomycin chlorambucil epirubicin 5-fluorouracil ifosfamide mitomycin methotrexate vincristine cisplatin and vinblastine. COPYRIGHT: (C)201...

The invention provides pharmaceutical compositions and method for inhibiting growth of prostatic adenocarcinoma stomach cancer breast cancer endometrial ovarian or other cancers of epithelial secretion or benign prostate hyperplasia (BPH). In one embodiment the pharmaceutical composition includes human rHuPSP94 antigenic portions thereof and functionally equivalent polypeptides thereof. In another embodiment the pharmaceutical composition includes a mixture of human rHuPSP94 antigenic portions t...