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WYETH CORP [US](9)
Wyeth(9)
GEN HOSPITAL CORP [US](8)
Cedars-sinai Medical Center(7)
The General Hospital Corporation(6)
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[药品] 包含 'Gefitinib '
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公开号
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1.
CN103626781A
2014/3/12
专利标题
:A kind of target anticancer molecule gefitinib phthalocyanine conjugates and preparation and application
专利权人
:
2.
US2014056910A1
2014/2/27
US201314057398
2013/10/18
专利标题
:THERAPEUTIC AGENT FOR CANCER HAVING REDUCED SENSITIVITY TO MOLECULAR TARGET DRUG AND PHARMACEUTICAL COMPOSITION FOR ENHANCING SENSITIVITY TO MOLECULAR TARGET DRUG
专利权人
:
KRINGLE PHARMA INC [JP]
;
Provided are a pharmaceutical composition which enhances the sensitivity of a cancer to a molecular target drug, such as gefitinib and erlotinib, wherein the cancer has resistance to the molecular target drug, and a cancer therapeutic agent effective against a cancer having resistance to a molecular target drug, such as gefitinib and erlotinib. The pharmaceutical composition comprising an HGF-MET receptor pathway inhibitor enhances the sensitivity of a cancer to a molecular target drug, such as ...
3.
CN103570633A
2014/2/12
专利标题
:The preparation method of gefitinib
专利权人
:
4.
KR20140015798A
2014/2/7
KR20120081011
2012/7/25
专利标题
:EFFECTIVE ANTICANCER DRUGS AGAINST GEFITINIB-RESISTANT HUMAN LUNG CANCER CELLS COMPRISING THE DAPHNANE DITERPENOID COMPOUND
专利权人
:
SNU R&DB FOUNDATION [KR]
;
5.
CN103536537A
2014/1/29
专利标题
:A kind of preparation method of lung target therapeutic agent gefitinib plga microsphere
专利权人
:
6.
US2014024620A1
2014/1/23
US201113878744
2011/10/14
专利标题
:Methods for Inhibiting Cell Proliferation in EGFR-Driven Cancers
专利权人
:
DALGARNO DAVID C [US]
;
SHAKESPEARE WILLIAM C [US]
;
ZHU XIAOTIAN [US]
;
RIVERA VICTOR M [US]
;
MIRET JUAN J [US]
;
ARIAD PHARMA INC [US]
;
The invention features a method for treating patients who have an EGFR-driven cancer, which is, or has become, refractory to a tyrosine kinase inhibitor, such as eriotinib and gefitinib, by administering a compound of formula (I) to the patient. The invention also features treating EGFR-driven cancers having an EGFR mutation identified herein.
7.
CN103524433A
2014/1/22
专利标题
:The synthetic method of a kind of gefitinib and intermediate thereof
专利权人
:
8.
KR20130134407A
2013/12/10
KR20120057883
2012/5/31
专利标题
:PROCESS FOR PREPARING GEFITINIB AND AN INTERMEDIATE USED FOR PREPARING THEREOF
专利权人
:
CHONG KUN DANG HOLDINGS CORP [KR]
;
9.
WO2013180403A1
2013/12/5
WO2013KR04024
2013/5/8
专利标题
:PROCESS FOR PREPARING GEFITINIB AND AN INTERMEDIATE USED FOR PREPARING THEREOF
专利权人
:
CHONG KUN DANG PHARM CORP [KR]
;
This invention relates to a method of preparing gefitinib and an intermediate used therein. In the method of preparing gefitinib, the production of an N-alkylated impurity can be suppressed via a simple process, and thus, gefitinib having high purity can be obtained with high efficiency without a complicated separation process such as chromatography, thereby enabling the effective mass production of gefitinib.
10.
CN103429262A
2013/12/4
CN2012811820
2012/3/15
专利标题
:Overcoming resistance to ERBB pathway inhibitors
专利权人
:
MERRIMACK PHARMACEUTICALS INC
;
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