Compositions and methods for the treatment of bladder cancer include intravesical dosage forms of a neoplastic agent and a permeation enhancer. The neoplastic agent may be valrubicin. Pharmaceutical compositions include intravesical dosage forms of a neoplastic agent complexed liposomes. Tight junction openers may be used for the effective delivery of the neoplastic agent.

The disclosure relates to compounds and compositions for bone formation fracture treatment bone grafting bone fusion cartilage maintenance and repair and methods related thereto. In certain embodiments the disclosure relates to compositions comprising one or more compound(s) disclosed herein such as clotrimazole honokiol magnolol tacrolimus pimecrolimus sirolimus everolimus temsirolimus spironolactone fluticasone fluticasone propionate fluticasone furoate linezolid telmisartan chlorambucil retin...

The invention relates to pharmaceutical compositions comprising an anthracycline for the treatment of an inflammatory skin disease, wherein both inflammation and infection are factors of the pathogenesis. The inflammatory skin disease may for example be acne. The compositions are in general prepared for direct administration to the skin. The anthracycline is an anthracycline, which does not induce necrosis and/or lasting tissue damage upon application to skin of human beings, for example valrubi...

The invention relates to pharmaceutical compositions comprising an anthracycline for the treatment of disease of the prostate including prostate cancer, prostatitis and benign prostate hyperplasia, an inflammatory bladder disease or for treatment of metastasis. The compositions are in general prepared for direct administration to the site of disease. The anthracycline is an anthracycline, which does not induce necrosis and/or lasting tissue damage upon application to skin of human beings, for ex...

Compositions and methods for the treatment of bladder cancer include intravesical dosage forms of a neoplastic agent and a permeation enhancer. The neoplastic agent may be valrubicin. Pharmaceutical compositions include intravesical dosage forms of a neoplastic agent complexed liposomes. Tight junction openers may be used for the effective delivery of the neoplastic agent.

Novel methods useful for treating a patient with bladder cancer such as superficial bladder cancer includes administering to the patient a therapeutically effective amount of valrubicin and trospium chloride.

Novel methods useful for treating a patient with bladder cancer such as superficial bladder cancer includes administering to the patient a therapeutically effective amount of valrubicin and trospium chloride.

Compositions and methods for the treatment of bladder cancer include intravesical dosage forms of a neoplastic agent and a permeation enhancer. The neoplastic agent may be valrubicin. Pharmaceutical compositions include intravesical dosage forms of a neoplastic agent complexed liposomes. Tight junction openers may be used for the effective delivery of the neoplastic agent.