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SUPERGEN INC [US](9)
WARNER LAMBERT CO [US](8)
RELIABLE BIOPHARMACEUTICAL CORPORATION(3)
MAYNE PHARMA PLC(2)
Supergen, Inc.(2)
REDKAR SANJEEV [US](2)
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SUPERGEN INC [US](1)
SANDS HOWARD [US](1)
专利信息
Translation Company
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[药品] 包含 'Pentostatin'
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公开号
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申请号
申请日
1.
CA2538857C
2013/6/11
专利标题
:Synthesis and manufacture of pentostatin and its precursors, analogs and derivatives
专利权人
:
Supergen, Inc.
;
Methods and compositions are provided for efficiently preparing and manufacturing pentostatin. Also provided are novel precursors of pentostatin pentostatin analogs and derivatives. In one aspect of the invention a method is provided for total chemical synthesis of pentostatin via a route of heterocyclic ring expansion. For example a heterocyclic pharmaceutical intermediate for drugs such as pentostatin e.g. the diazepinone precursor can be obtained efficiently through a ring expansion of an O-C...
2.
HK1128192A1
2013/4/5
HK20090106306
2009/7/14
专利标题
:SYNTHESIS AND MANUFACTURE OF PENTOSTATIN AND ITS PRECURSORS, ANALOGS AND DERIVATIVES
专利权人
:
MAYNE PHARMA PLC [GB]
;
3.
CN101343302B
2012/7/4
专利标题
:Synthetic and the manufacturing of pentostatin and precursor thereof, analogue and verivate
专利权人
:
MAYNE PHARMA PLC
;
4.
CN102453065A
2012/5/16
CN20101526100
2010/10/29
专利标题
:Method for removing impurities in pentostatin fermentation liquid
专利权人
:
SHANGHAI INST PHARM INDUSTRY
;
5.
CZ302908B6
2012/1/18
CZ20010000932
1999/9/9
专利标题
:Pharmaceutical composition containing cyclopeptide and chemotherapeutic agent
专利权人
:
MERCK PATENT GMBH
;
In the present invention there is disclosed a pharmaceutical composition containing cyclopeptide cyclo-(Arg-Gly-Asp-D-Phe-NMe-Val) and/or a physiologically acceptable salt thereof and at least one chemotherapeutic agent and/or physiologically acceptable salts thereof being selected from the group consisting of a) alkylating agents selected from a group consisting of busulfan carboplatin carmustine cisplatin cyclophosphamide dacarbazine ifosfamide and lomustine b) antibiotics selected from a grou...
6.
US2010261666A1
2010/10/14
US20100760381
2010/4/14
专利标题
:COMPOSITIONS AND METHODS FOR THE TREATMENT OF MYOCARDIAL DYSFUNCTION ASSOCIATED WITH SIRS OR SEPSIS
专利权人
:
UNIV ILLINOIS [US]
;
Provided are compositions and methods for the treatment of myocardial dysfunction associated with SIRS or sepsis, which methods comprise the administration to a patient in need thereof of a composition comprising one or more adenosine deaminase (ADA) inhibitor and/or one or more xanthine oxidase (XO) inhibitor. Exemplified herein are methods for the treatment of myocardial dysfunction, which methods comprise the administration of a composition comprising the ADA inhibitor pentostatin and/or a co...
7.
CN101798330A
2010/8/11
CN20091096059
2009/2/6
专利标题
:Extraction and purification method of pentostatin
专利权人
:
HANGZHOU HUADONG MEDICINE GROUP BIOTECHNOLOGY INST CO LTD
;
8.
EP1670809A4
2009/12/23
专利标题
:Synthesis and manufacture of pentostatin and its precursors, analogs and derivatives
专利权人
:
MAYNE PHARMA PLC
;
9.
HK1096688A1
2009/7/17
HK20070104190
2007/4/20
专利标题
:SYNTHESIS AND MANUFACTURE OF PENTOSTATIN AND ITS PRECURSORS, ANALOGS AND DERIVATIVES
专利权人
:
MAYNE PHARMA PLC [GB]
;
Methods and compositions are provided for efficiently preparing and manufacturing pentostatin. Also provided are novel precursors of pentostatin, pentostatin analogs and derivatives. In one aspect of the invention, a method is provided for total chemical synthesis of pentostatin via a route of heterocyclic ring expansion. For example, a heterocyclic pharmaceutical intermediate for drugs such as pentostatin, e.g., the diazepinone precursor, can be obtained efficiently through a ring expansion of ...
10.
CN101343302A
2009/1/14
CN20081133620
2004/9/15
专利标题
:Synthesis and manufacture of pentostatin and its precursors, analogs and derivatives
专利权人
:
SUPERGEN INC [GB]
;
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