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ONCOPEPTIDES AB(9)
UNIV COLORADO STATE RES FOUND [US](9)
WELLCOME FOUND [GB](8)
The Wellcome Foundation Limited(6)
JINAN SHUAIHUA PHARMACEUTICAL [CN](6)
Prolx Pharmaceuticals Corporation(5)
Topotarget Uk Limited(4)
PROLX PHARMACEUTICALS CORP [US](4)
WELLCOME FOUND(3)
SANOFI AVENTIS [FR](3)
专利信息
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[药品] 包含 'Melphalan '
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公开号
公开日
申请号
申请日
1.
EP2711000A1
2014/3/26
EP20130156234
2013/2/21
专利标题
:Targeted liposomes
专利权人
:
Georgetown University
;
The present invention is in the field of drug delivery and specifically cationic liposome-based drug delivery. In embodiments this invention provides methods of making ligand-targeted (e.g. antibody- or antibody fragment-targeted) liposomes useful for the delivery of liposomes to tumors including brain tumors. In embodiments the liposomes deliver temozolomide across the blood-brain barrier for treatment of primary or metastatic brain tumors. Additional cancers that can be treated with the liposo...
2.
CN102030671B
2014/2/19
专利标题
:The preparation method of pharmaceutical grade melphalan and hydrochloric acid one salt thereof, disalt
专利权人
:
Zhejiang Chempacific Chemical Co., Ltd.
;
3.
US8575385B2
2013/11/5
专利标题
:Process of making optically pure melphalan
专利权人
:
NAVINTA LLC
;
This invention provides a process of making optically pure melphalan of the formula by hydroxyethylation in a regioselective manner of the aromatic amino group rather than the glycinic amino group.
4.
CN102167711B
2013/8/7
专利标题
:99mtco nuclear mark melphalan dithiocarbamate complexes and preparation method and application
专利权人
:
Beijing Normal University
;
5.
PL397663A1
2013/7/8
PL20110397663
2011/12/30
专利标题
:The new melphalan derivatives, processes for their preparation, pharmaceutical composition containing them and the medical use
专利权人
:
INST BIOTECHNOLOGII I ANTYBIOTYKOW [PL]
;
6.
AU2006313517B2
2013/6/27
AU20060313517
2006/11/10
专利标题
:Histone deacetylase (hdac) inhibitors (pxd101) for the treatment of cancer alone or in combination with chemotherapeutic agent
专利权人
:
Topotarget Uk Limited
;
The present invention relates generally to methods for treating cancer. In one respect the present invention relates to a method of treating a hematological cancer (e.g. multiple myeloma leukemia lymphoma) comprising administering to a patient in need thereof a therapeutically effective amount of a histone deacetylase inhibitor for example a histone deacetylase (HDAC) inhibitor as described herein for example PXD-101. In another respect the present invention relates to a method of treating cance...
7.
AU2013205999A1
2013/6/13
AU20130205999
2013/5/23
专利标题
:Histone deacetylase (hdac) inhibitors (pxdlol) for the treatment of cancer alone or in combination with chemotherapeutic agent
专利权人
:
Topotarget Uk Limited
;
The present invention relates generally to methods for treating cancer. In one respect the present invention relates to a method of treating a hematological cancer (e.g. multiple myeloma leukemia lymphoma) comprising administering to a patient in need thereof a therapeutically effective amount of a histone deacetylase inhibitor for example a histone deacetylase (HDAC) inhibitor as described herein for example PXD-101. In another respect the present invention relates to a method of treating cance...
8.
EP2599484A1
2013/6/5
EP20110803180
2011/7/4
专利标题
:INJECTABLE PHARMACEUTICAL FORMULATION OF MELPHALAN
专利权人
:
ERIOCHEM S A [AR]
;
An injectable pharmaceutical formulation of Melphalan comprising a solid composition of melphalan hydrochloride lyophilized with a content of impurities up to 1.3 % (p/p)and a pH buffer solution
9.
US2013131174A1
2013/5/23
US201113808728
2011/7/4
专利标题
:INJECTABLE PHARMACEUTICAL FORMULATION OF MELPHALAN
专利权人
:
CASTILLO JOSE [AR]
;
ITURRASPE JOSE BERNARDO [AR]
;
NUNEZ JOSE LUCIO [AR]
;
ERIOCHEM [AR]
;
An injectable pharmaceutical formulation of Melphalan comprising a solid composition of melphalan hydrochloride lyophilized with a content of impurities up to 1.3% (p/p)and a pH buffer solution
10.
US20130131174A1
2013/5/23
专利标题
:Injectable pharmaceutical formulation of melphalan
专利权人
:
Eriochem
;
An injectable pharmaceutical formulation of Melphalan comprising a solid composition of melphalan hydrochloride lyophilized with a content of impurities up to 1.3% (p/p)and a pH buffer solution; a process to prepare said solid composition. Also a reconstituted solution of melphalan comprising a solid composition of melphalan lyophilized reconstituted wherein said solution is aqueous a perfusion free of organic solvent and a kit.
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