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  • [药品] 包含 'Melphalan '
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标题标题2专利权人发明人附图摘要摘要2优先权号IPC专利类型
首页123456下页尾页185 条记录, 当前第1/19页。
公开号 公开日 申请号 申请日
1. EP2711000A1 2014/3/26 EP20130156234 2013/2/21
专利标题:Targeted liposomes 法律状态
专利权人Georgetown University;
The present invention is in the field of drug delivery and specifically cationic liposome-based drug delivery. In embodiments this invention provides methods of making ligand-targeted (e.g. antibody- or antibody fragment-targeted) liposomes useful for the delivery of liposomes to tumors including brain tumors. In embodiments the liposomes deliver temozolomide across the blood-brain barrier for treatment of primary or metastatic brain tumors. Additional cancers that can be treated with the liposo...


2. CN102030671B 2014/2/19
专利标题:The preparation method of pharmaceutical grade melphalan and hydrochloric acid one salt thereof, disalt 法律状态


3. US8575385B2 2013/11/5
专利标题:Process of making optically pure melphalan 法律状态
专利权人NAVINTA LLC;
This invention provides a process of making optically pure melphalan of the formula by hydroxyethylation in a regioselective manner of the aromatic amino group rather than the glycinic amino group.


4. CN102167711B 2013/8/7
专利标题:99mtco nuclear mark melphalan dithiocarbamate complexes and preparation method and application 法律状态
专利权人Beijing Normal University;


5. PL397663A1 2013/7/8 PL20110397663 2011/12/30
专利标题:The new melphalan derivatives, processes for their preparation, pharmaceutical composition containing them and the medical use 法律状态


6. AU2006313517B2 2013/6/27 AU20060313517 2006/11/10
专利标题:Histone deacetylase (hdac) inhibitors (pxd101) for the treatment of cancer alone or in combination with chemotherapeutic agent 法律状态
专利权人Topotarget Uk Limited;
The present invention relates generally to methods for treating cancer. In one respect the present invention relates to a method of treating a hematological cancer (e.g. multiple myeloma leukemia lymphoma) comprising administering to a patient in need thereof a therapeutically effective amount of a histone deacetylase inhibitor for example a histone deacetylase (HDAC) inhibitor as described herein for example PXD-101. In another respect the present invention relates to a method of treating cance...


7. AU2013205999A1 2013/6/13 AU20130205999 2013/5/23
专利标题:Histone deacetylase (hdac) inhibitors (pxdlol) for the treatment of cancer alone or in combination with chemotherapeutic agent 法律状态
专利权人Topotarget Uk Limited;
The present invention relates generally to methods for treating cancer. In one respect the present invention relates to a method of treating a hematological cancer (e.g. multiple myeloma leukemia lymphoma) comprising administering to a patient in need thereof a therapeutically effective amount of a histone deacetylase inhibitor for example a histone deacetylase (HDAC) inhibitor as described herein for example PXD-101. In another respect the present invention relates to a method of treating cance...


8. EP2599484A1 2013/6/5 EP20110803180 2011/7/4
专利标题:INJECTABLE PHARMACEUTICAL FORMULATION OF MELPHALAN 法律状态
专利权人ERIOCHEM S A [AR];
An injectable pharmaceutical formulation of Melphalan comprising a solid composition of melphalan hydrochloride lyophilized with a content of impurities up to 1.3 % (p/p)and a pH buffer solution


9. US2013131174A1 2013/5/23 US201113808728 2011/7/4
专利标题:INJECTABLE PHARMACEUTICAL FORMULATION OF MELPHALAN 法律状态
An injectable pharmaceutical formulation of Melphalan comprising a solid composition of melphalan hydrochloride lyophilized with a content of impurities up to 1.3% (p/p)and a pH buffer solution


10. US20130131174A1 2013/5/23
专利标题:Injectable pharmaceutical formulation of melphalan 法律状态
专利权人Eriochem;
An injectable pharmaceutical formulation of Melphalan comprising a solid composition of melphalan hydrochloride lyophilized with a content of impurities up to 1.3% (p/p)and a pH buffer solution; a process to prepare said solid composition. Also a reconstituted solution of melphalan comprising a solid composition of melphalan lyophilized reconstituted wherein said solution is aqueous a perfusion free of organic solvent and a kit.



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