PROBLEM TO BE SOLVED: To provide a method for treating cervical cancer or cells infected with human papilloma virus. SOLUTION: Interleukin-20 (IL-20) can be administered alone or in conjunction with radiation or chemotherapeutic agents or surgical excision of the involved cells or lesions. The chemotherapeutic agent is selected from the group consisting of bleomycin chlorambucil epirubicin 5-fluorouracil ifosfamide mitomycin methotrexate vincristine cisplatin and vinblastine. COPYRIGHT: (C)201...

The present disclosure concerns complexes of 4-hydroperoxy ifosfamide. In one embodiment the complexes can be represented by the formula wherein A represents an ammonium species selected from the conjugate acid of a basic amino acid quaternary ammonium aliphatic ammonium heterocyclic ammonium aromatic ammonium substituted and unsubstituted pyridinium guanidinium and amidinium and wherein X and Y independently represent leaving groups. Also disclosed herein are methods for making such compounds a...

La présente invention concerne une nouvelle approche pour le traitement de la mucoviscidose qui fait intervenir la chimiothérapie notamment anti-cancéreuse. Elle a pour objet l'utilisation pour le traitement de la mucoviscidose d'au moins un produit dont l'administration à un patient conduit à l'expression ou à la surexpression d'un composé transporteur ABC notamment transporteur de glutathion. De préférence les produits utilisés sont des produits anti-cancéreux dont l'administration conduit à l...

The invention relates to a method for purifying a reaction product containing 3-aminopropanol, said reaction product being produced in the reaction of ethylene cyanohydrin with hydrogen in the presence of ammonia, characterized in that the reaction product containing 3-aminopropanol is distilled in two or more stages, wherein the ammonia content of the reaction product containing 3-aminopropanol is 1 wt% or less before the reaction product is introduced into the first distillation stage and the ...

PURPOSE: A pharmaceutical composition containing 3-caffeoyl-4-dihydrocaffeoyl quinic acid(CDCQ) is provided to suppress cell basal lamina digesting enzyme MMP-2 and MMP-9 activities and prevent cancer cell metastasis. CONSTITUTION: A pharmaceutical composition for suppressing cancer metastasis contains 3-caffeoyl-4-dihydrocaffeoylquinic acid. The composition suppresses activity of MMP-2(matrix metalloprotease-2) or MMP-9(matrix metalloprotease-9). A health food for preventing metastasis contains...

Temperature sensitive immunoliposomes are provided to improve selectivity of drugs to target cells by binding an antibody recognizing an epitope specific to the target cell so that the drugs are transported to target cells such as cancer cells or target organs to kill cancer cells. Temperature-sensitive immunoliposomes consist of phospholipids of dipalmitoylphosphatidylcholine(DPPC) dimyristoylphosphatidylcholine(DMPC) and distearoylphosphatidylcholine(DSPC) and dioleoylphosphatidylethanolamine(...

In the present invention there is disclosed a pharmaceutical composition containing cyclopeptide cyclo-(Arg-Gly-Asp-D-Phe-NMe-Val) and/or a physiologically acceptable salt thereof and at least one chemotherapeutic agent and/or physiologically acceptable salts thereof being selected from the group consisting of a) alkylating agents selected from a group consisting of busulfan carboplatin carmustine cisplatin cyclophosphamide dacarbazine ifosfamide and lomustine b) antibiotics selected from a grou...