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标题标题2专利权人发明人附图摘要摘要2优先权号IPC专利类型
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公开号 公开日 申请号 申请日
1. WO2014036548A1 2014/3/6 WO2013US57807 2013/9/3
专利标题:MACROMOLECULAR PRODRUGS FOR HARD TISSUE AND METHODS OF USE THEREOF 法律状态
Compositions for intravenous administration and methods for treating bone diseases, disorders, and fractures comprising macromolecular prodrugs of hydrophobic bone anabolic agents are provided. Specifically, novel macromolecular amphiphilic prodrugs wherein at least three molecules of simvastatin are conjugated to polyethylene glycol, which spontaneously form micelles in aqueous solutions are provided.


2. CN103585146A 2014/2/19 CN20131554342 2013/11/9
专利标题:The pharmaceutical composition of simvastatin 法律状态
专利权人


3. CN103550205A 2014/2/5 CN20131554687 2013/11/9
专利标题:Simvastatin solid composite 法律状态
专利权人


4. EP1533308B1 2014/1/15 EP20040023298 1999/12/10
专利标题:A process for producing a simvastatin precursor 法律状态
专利权人Kaneka Corporation;


5. CN103494818A 2014/1/8 CN20131476959 2013/10/14
专利标题:A kind of niacin simvastatin sustained-release sheet and preparation method thereof 法律状态
专利权人


6. CN103432103A 2013/12/11 CN20131418155 2013/9/11
专利标题:Compound nicotinic acid sustained-release capsules and preparation method thereof 法律状态
专利权人UNIV CHINA PHARMA;


7. US2013302284A1 2013/11/14 US201113988768 2011/11/22
专利标题:MODULATING ONCOLYTIC VSV AND UPREGULATING RAE1 AND NUP98 WITH STATINS 法律状态
Simvastatin is used to modulate VSV infection at the level of viral replication. Both lipid-lowering and pleiotropic cellular effects of simvastatin are exploited in the modulation. Simvastatin upregulates the expression of Rae1 and Nup98, therefore altering normal cellular mRNA distribution and reverting VSV's mRNA export block. Furthermore, simvastatin causes redistribution of Flotillin-1, which affects VSV replication/budding. Simvastatin is further used as a neoadjuvant for the selective mod...


8. CN103356494A 2013/10/23 CN20131142869 2013/4/23
专利标题:High-stability simvastatin tablets and preparation method thereof 法律状态


9. CN103360357A 2013/10/23 CN20131339700 2013/8/7
专利标题:A simvastatin-gliclazide co-amorphous compound 法律状态


10. EP2370061B1 2013/10/23 EP20090760531 2009/11/30
专利标题:Pharmaceutical composition comprising ezetimibe and simvastatin 法律状态
专利权人Lek Pharmaceuticals D.d.;



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