A method and composition are provided for the treatment of an anorectal disorder and for controlling the pain associated therewith. The method comprises administering to a subject in need of such treatment therapeutically effective amounts of a calcium channel blocker either alone or together with a nitric oxide donor. Amlodipine anipamil barnidipine benidipine bepridil darodipine diltiazem efonidipine felodipine isradipine lacidipine lercanidipine lidoflazine manidipine mepirodipine nicardipine...