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ESSENTIALIS INC(7)
NEUROTEC PHARMA S L [ES](6)
NEUROTEC PHARMA S L [ES](6)
UNIV NICE SOPHIA ANTIPOLIS [FR](4)
ESSENTIALIS INC [US](4)
CENTRE NAT RECH SCIENT [FR](4)
PAULSEN ELSA P [US](4)
SUNSTAR INC(3)
SHISEIDO CO LTD(3)
COOEPERATIEVE MIRZORG U A ARNH [NL](3)
专利信息
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公开号
公开日
申请号
申请日
1.
US2014057877A1
2014/2/27
US201113276133
2011/10/18
专利标题
:Therapeutic polyamine compositions and their synthesis
专利权人
:
MURPHY MICHAEL A [US]
;
MALACHOWSKI MITCHELL R [US]
;
This invention relates to a process of synthesis and composition of open chain (ring), closed ring, linear branched and or substituted polyamines, polyamine derived tyrosine phosphatase inhibitors and PPAR partial agonists/partial antagonists via a series of substitution reactions and optimizing the bioavailability and biological activities of the compounds. Polyamines prevent the toxicity of neurotoxins and diabetogenic toxins including paraquat, methyphenyl pyridine radical, rotenone, diazoxid...
2.
US2013309301A1
2013/11/21
US201213671418
2012/11/7
专利标题
:SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF
专利权人
:
ESSENTIALS INC [US]
;
ESSENTIALIS INC [US]
;
Provided are immediate or prolonged administration of certain salts of KATP channel openers such as diazoxide to a subject to achieve novel pharmacodynamic, pharmacokinetic, therapeutic, physiological, metabolic and compositional outcomes in the treatment of diseases or conditions involving KATP channels. Also provided are pharmaceutical formulations, methods of administration and dosing of the salts that achieve these outcomes and reduce the incidence of adverse effects in treated individuals. ...
3.
WO2013130411A1
2013/9/6
WO2013US27676
2013/2/25
专利标题
:SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF
专利权人
:
ESSENTIALIS INC [US]
;
Provided are immediate or prolonged administration of certain salts of KATP channel openers such as diazoxide to a subject to achieve novel pharmacodynamic, pharmacokinetic, therapeutic, physiological, metabolic and compositional outcomes in the treatment of diseases or conditions involving KATP channels. Also provided are pharmaceutical formulations, methods of administration and dosing of the salts that achieve these outcomes and reduce the incidence of adverse effects in treated individuals. ...
4.
US2013225806A1
2013/8/29
US201313846542
2013/3/18
专利标题
:SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF
专利权人
:
COWEN NEIL M [US]
;
YAMOUT KHALED A [US]
;
ESSENTIALIS INC [US]
;
Provided are immediate or prolonged administration of certain salts of KATP channel openers such as diazoxide to a subject to achieve novel pharmacodynamic, pharmacokinetic, therapeutic, physiological, metabolic and compositional outcomes in the treatment of diseases or conditions involving KATP channels. Also provided are pharmaceutical formulations, methods of administration and dosing of the salts that achieve these outcomes and reduce the incidence of adverse effects in treated individuals. ...
5.
CN103172592A
2013/6/26
CN2013141514
2006/12/20
专利标题
:Salts of potassium atp channel openers and uses thereof
专利权人
:
ESSENTIALIS INC
;
6.
EP2605776A1
2013/6/26
EP20110743249
2011/8/16
专利标题
:DIAZOXIDE FOR USE IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS)
专利权人
:
NEUROTEC PHARMA S L [ES]
;
7.
US2013143873A1
2013/6/6
US201113817381
2011/8/16
专利标题
:Diazoxide For Use In The Treatment Of Amyotrophic Lateral Sclerosis (ALS)
专利权人
:
PUGLIESE MARCO [ES]
;
ESPINOSA PARRILLA JUAN FRANCISCO [ES]
;
VIRGILI TRESERRES NOEMI [ES]
;
MANCERA AROCA PILAR [ES]
;
PASTEN ZAMORANO ANDREA [ES]
;
MAHY GEHENNE JOSETTE-NICOLE [ES]
;
RODRIGUEZ ALLUE MANUEL [ES]
;
NEUROTEC PHARMA S L [ES]
;
The invention relates to the diazoxide or a pharmaceutically acceptable salt thereof for use as a medicament at low doses to treat amyotrophic lateral sclerosis.
8.
US20130143873A1
2013/6/6
US13/817381
2011/8/16
专利标题
:Diazoxide for use in the treatment of amyotrophic lateral sclerosis (als)
专利权人
:
Neurotec Pharma, S.l.
;
The invention relates to the diazoxide or a pharmaceutically acceptable salt thereof for use as a medicament at low doses to treat amyotrophic lateral sclerosis.
9.
MX2013004214A
2013/6/5
MX20130004214
2013/4/15
专利标题
:USE OF MONOAMINE OXIDASE INHIBITORS TO IMPROVE EPITHELIAL BIOLOGY.
专利权人
:
PROCTER & GAMBLE [US]
;
The invention provides a method for improving hair biology, e.g., hair growth. The method comprises administering to a subject a monoamine oxidase inhibitor and a vasodilator, a zinc salt of a carboxylic acid, a xanthine compound, pyrithione or a salt thereof, saponin, tritapene, crataegolic acid, celastrol, asiatic acid, an inhibitor of 5-alpha-reductase, 1,4-methyl-4-azasteroid, an androgen receptor antagonist, azelaic acid or a derivate thereof, cyclosporin, triiodothyronine, diazoxide, retin...
10.
US2013040942A1
2013/2/14
US201213543665
2012/7/6
专利标题
:SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF
专利权人
:
ESSENTIALIS INC
;
COWEN NEIL M [US]
;
DUKES IAIN [US]
;
Provided are immediate or prolonged administration of certain salts of KATP channel openers such as diazoxide to a subject to achieve novel pharmacodynamic, pharmacokinetic, therapeutic, physiological, metabolic and compositional outcomes in the treatment of diseases or conditions involving KATP channels. Also provided are pharmaceutical formulations, methods of administration and dosing of the salts that achieve these outcomes and reduce the incidence of adverse effects in treated individuals. ...
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