The invention relates to transdermal compositions including nifedipine, pentoxifylline, ketamine hydrochloride, gabapentin, lidocaine, and prilocaine that may be used to treat conditions such as circulatory disorders and peripheral neuropathy. Additionally, methods of the invention are directed to treating conditions such as circulatory disorders, peripheral neuropathy, wound healing, blood flow issues, or the like, comprising the steps of transdermal or topical administration of the composition...

PROBLEM TO BE SOLVED: To provide a novel arteriosclerosis drug that controls infiltration of macrophage into an artery and is thereby capable of controlling thickening and fibrosis of aortic tunica media. SOLUTION: The arteriosclerosis drug includes nitroso nifedipine and a nitroso nifedipine derivative such as nitroso-nisoldipine nitroso-nimodipine nitroso-nicardipine and nitroso-nitrendipine nitroso nifedipine as active ingredients. The drug can control infiltration of macrophage into an arte...

601343 Disclosed is an oral liquid pharmaceutical composition which is a solution comprising: a) nifedipine in an amount comprised between 0.1% and 1% w/w