The present invention relates to stable fixed dose topical formulations comprising an antiacne agent and an antibiotic which exhibit storage stability at a temperature of about 40� C. and relative humidity of about 75% for a period of at least 3 months. Particularly the present invention relates to stable fixed dose topical formulations comprising therapeutically effective amounts of (a) adapalene-containing microspheres and (b) clindamycin a process for their preparation thereof and their use f...

Adapalene or a pharmaceutically acceptable salt thereof formulated into a pharmaceutical composition is useful for reducing the number of acne lesions via daily topical application in combination or in association with benzoyl peroxide (BPO); such treatment may be via administration of a pharmaceutical composition combining adapalene and BPO or by a concomitant application of two pharmaceutical compositions one containing adapalene and the other containing BPO.

Adapalene or a pharmaceutically acceptable salt thereof formulated into a pharmaceutical composition is useful for reducing the number of acne lesions, via daily topical application, in combination or in association with benzoyl peroxide (BPO)

Intermediate compositions and in particular gels and suspensions for a foam composition comprising adapalene are described. Also described, is the dermatological use of such compositions.

The present invention relates to a method for treating reducing or preventing acne. In particular the present invention relates to methods for reducing the total number incidence and severity of acne lesions on the skin which includes both inflammatory and non-inflammatory lesions. Further the invention relates to reducing the incidence and severity of adverse events resulting from topical application of anti-acne agents resulting in improvement of skin tone. The method includes administering a ...

Intermediate compositions and in particular gels and suspensions for a foam composition comprising adapalene are described. Also described is the dermatological use of such compositions.