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标题标题2专利权人发明人附图摘要摘要2优先权号IPC专利类型
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公开号 公开日 申请号 申请日
1. CN103408535A 2013/11/27 CN20131349877 2013/8/13
专利标题:Synthetic process of Almotriptan intermediate 5-bromo-3-(N-methyl pyrroline-2-methyl)-1H-indole 法律状态


2. CN103156816A 2013/6/19 CN20111427472 2011/12/19
专利标题:Almotriptan drug absorbed through mouth mucosa 法律状态


3. EP1907377B1 2013/4/24 EP20060780542 2006/7/21
专利标题:A process for the preparation of almotriptan 法律状态


4. CN102827062A 2012/12/19 CN20121342824 2012/9/17
专利标题:Method for preparing almotriptan malate 法律状态


5. CN102775392A 2012/11/14 CN20111123073 2011/5/12
专利标题:N-protection-3, 5-disubstituted indole derivative, its preparation method and application 法律状态


6. CN102775391A 2012/11/14 CN20111123054 2011/5/12
专利标题:Method for preparing migraine resistant medicine Almotriptan 法律状态


7. CN102775342A 2012/11/14 CN20111123085 2011/5/12
专利标题:Preparation method of anti-migraine drug Almotriptan 法律状态


8. US2012232123A1 2012/9/13 US201013510650 2010/11/19
专利标题:LIQUID PHARMACEUTICAL COMPOSITIONS 法律状态
Aqueous liquid pharmaceutical composition comprising a) almotriptan and b) at least one compound selected from i) 1'-methyl-5-((pyrrolidin-1-ylsulfonyl)methyl)spiro[indoline-3,3'-pyrrolidin]-2-ol, and ii) 3-(2-(dimethylamino)ethyl)-5-((pyrrolidin-1-ylsulfonyl)methyl)-1H-indol-2-ol.


9. EA016759B1 2012/7/30 EA20090001626 2008/6/13
专利标题:Method for the preparation of high purity almotriptan 法律状态
专利权人Zentiva, A.s.;
A method for the preparation and purification of the substance of formula (I) i.e. 3-[2-(dimethylamino)ethyl]-5-(1-pyrrolidinylsulfonylmethyl)-1H-indole which comprises: (a) conversion of 4-(1-pyrrolidinylsulfonylmethyl)phenylhydrazine of formula (III) by reaction with an organic or inorganic acid to a salt that is insoluble or poorly soluble in water which is converted to 3-(2-aminoethyl)-5-(1-pyrrolidinylsulfonylmethyl)indole of formula (VII) which is further converted without isolation to a s...


10. CN102573795A 2012/7/11 CN2010847729 2010/11/19
专利标题:Liquid pharmaceutical compositions 法律状态
专利权人ALMIRALL SA;



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