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Medimmune Oncology, Inc.(41)
Medimmune, Llc(21)
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[药品] 包含 'Amifostine'
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公开号
公开日
申请号
申请日
1.
CN103509048A
2014/1/15
专利标题
:A kind of preparation method of green amifostine
专利权人
:
2.
CN103509049A
2014/1/15
专利标题
:A kind of method of preparing medicinal amifostine
专利权人
:
3.
CN103396439A
2013/11/20
CN20131331345
2013/8/1
专利标题
:Synthetic method for thiophosphate cell protective agent-amifostine
专利权人
:
UNIV SHENYANG PHARMACEUTICAL
;
4.
CN102399238B
2013/6/12
专利标题
:The preparation method of amifostine
专利权人
:
Kaifeng Mingren Pharmaceutical Co.,ltd.
;
5.
US2013090312A1
2013/4/11
US201213689652
2012/11/29
专利标题
:METHODS OF USE RELATED TO XEROSTOMIA
专利权人
:
MEDIMMUNE LLC [US]
;
MEDIMMUNE LLC [US]
;
The present invention relates to new uses of thermally stable, crystalline S-2-(3-aminopropylamino)ethyl dihydrogen phosphorothioate, (amifostine) and other aminothiol compounds to treat and reverse toxicities caused by radiation treatment. In particular, the invention provides a method for treating or preventing xerostomia associated with the administration of radiation treatment of head and neck cancer.
6.
CN102659836A
2012/9/12
CN20121110491
2012/4/16
专利标题
:Method for preparing amifostine
专利权人
:
NANJING CHENGONG PHARMACEUTICAL CO LTD
;
7.
US2012082736A1
2012/4/5
US201113244594
2011/9/25
专利标题
:Small-molecule TNF modulator to reduce the side effects of chemotherapy and radiotherapy
专利权人
:
SHAW JIAJIU [US]
;
GENEBLUE CORP [US]
;
21ST CENTURY THERAPEUTICS INC [US]
;
Cancer patients treated by chemotherapy and/or radiotherapy often suffer serious side effects. Currently, there is only one FDA approved and used as both a chemoprotector and a radioprotector, amifostine, which is associated with significant problems. Disclosed in the present invention are novel methods of using UTL-5g as both a chemoprotector and radioprotector for treating cancer patients in addition to other related methods.
8.
CN102399238A
2012/4/4
CN20111431844
2011/12/21
专利标题
:Preparation method for amifostine
专利权人
:
KAIFENG MINGREN PHARMACEUTICAL CO LTD
;
9.
CN102210694A
2011/10/12
CN2011191377
2011/4/12
专利标题
:Oral amifostine preparation and preparation method thereof
专利权人
:
SHANGHAI CHANGZHENG HOSPITAL
;
10.
EP1764103A3
2011/8/24
专利标题
:Crystalline amifostine compositions and methods for the preparation and use of same
专利权人
:
Medimmune Oncology, Inc.
;
The present invention relates to a sterile stable vacuum dried crystalline amifostine composition and optionally pharmaceutically acceptable excipient(s). Typically the crystalline compositions of the present invention exhibit enhanced stability at temperatures ranging from about 4°C to about ambient temperature for a period of at least 2 years relative to existing solid vacuum dried amorphous amifostine preparations. The reconstituted compositions of the present invention are suitable for admin...
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