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公开号
公开日
申请号
申请日
1.
US2014011817A1
2014/1/9
US201313972558
2013/8/21
专利标题
:COMPOSITION FOR REDUCING NERVOUS SYSTEM INJURY AND METHOD OF MAKING AND USE THEREOF
专利权人
:
MOREHOUSE SCHOOL OF MEDICINE [US]
;
This application discloses a composition comprising an amiloride and/or an amiloride analog which can be used for reducing nerve injury or nervous system injury in a subject. The formulation of such composition is also disclosed. The application further directs to methods for treating nerve injury or nervous system injury by administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising amiloride, an amiloride analog or a pharmaceutically acceptable sa...
2.
CN103251954A
2013/8/21
CN20131189925
2013/5/22
专利标题
:A kind for the treatment of diabetes compound medicine that reduces the rosiglitazone side effect and preparation method thereof
专利权人
:
3.
EP1121128B1
2013/4/17
专利标题
:Amiloride analogues for use in a method of modulating ion channel functional activity and treating hiv infection
专利权人
:
Biotron Limited
;
4.
CN101559059B
2012/12/5
专利标题
:A kind of pharmaceutical composition that contains amiloride hydrochloride and preparation method thereof
专利权人
:
Beijing Venturepharm Technology Co., Ltd.
;
5.
CN102793703A
2012/11/28
CN20111136340
2011/5/25
专利标题
:Medicinal composition of amiloride hydrochloride and cyclopenthiazide and preparation method for medicinal composition
专利权人
:
SUZHOU HONGRUI MEDICAL TECHNOLOGY CO LTD
;
6.
EP2520574A1
2012/11/7
EP20120173703
2008/12/9
专利标题
:Amiloride analogues substituted on the cyclic guanidine moiety as ENaC blockers for treating respiratory diseases
专利权人
:
NOVARTIS AG [CH]
;
A compound of Formula I in free or salt or solvate form, where R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 and R 11 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. In particular, airway diseases like COPD and cystic fibrosis are treatable, but also inflammatory and allergic diseases. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds ar...
7.
US2012108494A1
2012/5/3
US20080671824
2008/8/1
专利标题
:INHIBITORS OF INTRACELLULAR UROKINASE PLASMINOGEN ACTIVATOR AND METHODS OF USE THEREOF
专利权人
:
GORIN FREDRIC A [US]
;
NANTZ MICHAEL H [US]
;
UNIV CALIFORNIA [US]
;
The present invention provides compositions comprising amiloride amino acid and peptide conjugates. Efficient methods are also provided for administering the compositions for treating cancer and for delivering an amiloride conjugate into cancer cells in a subject in need thereof.
8.
EP2444120A1
2012/4/25
EP20110184004
2008/12/9
专利标题
:Spirocyclic amiloride analogues as ENac blockers
专利权人
:
NOVARTIS AG [CH]
;
A compound of Formula I in free or salt or solvate form, where R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 and R 11 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
9.
JP2011231023A
2011/11/17
JP20100100248
2010/4/23
专利标题
:INFILTRATION INHIBITOR
专利权人
:
UNIV EHIME
;
PROBLEM TO BE SOLVED: To provide an infiltration inhibitor capable of suppressing effectively infiltration of various cancer cells.
10.
CN101396560B
2011/11/9
CN20071046754
2007/9/28
专利标题
:The pharmaceutical composition and the application thereof of treatment multicystic kidney disease
专利权人
:
Changzhou High-tech Industry Development Zone Thre
;
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