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BRISTOL-MYERS SQUIBB COMPANY(6)
PFIZER [US](6)
PFIZER [US](5)
SQUIBB BRISTOL MYERS CO [US](5)
SQUIBB BRISTOL MYERS CO [US](4)
SQUIBB BRISTOL MYERS CO(3)
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BRISTOL-MYERS SQUIBB CO(2)
Pfizer Inc.(2)
Cadila Healthcare Limited(2)
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公开号
公开日
申请号
申请日
1.
US2014058107A1
2014/2/27
US201214110966
2012/6/7
专利标题
:APIXABAN PREPARATION PROCESS
专利权人
:
VLADISKOVIC CHIARA [IT]
;
ATTOLINO EMANUELE [IT]
;
LOMBARDO ALESSANDRO [IT]
;
TAMBINI SIMONE [IT]
;
DIPHARMA FRANCIS SRL [IT]
;
Process for the preparation of apixaban and intermediates useful for the preparation thereof.
2.
US20140058107A1
2014/2/27
专利标题
:Apixaban preparation process
专利权人
:
Dipharma Francis S.r.i.
;
Process for the preparation of apixaban and intermediates useful for the preparation thereof.
3.
WO2013164839A3
2014/2/27
专利标题
:Amorphous form of apixaban, process of preparation and compositions thereof
专利权人
:
Cadila Healthcare Limited
;
The present invention discloses an amorphous form of apixaban process of preparation and compositions thereof.
4.
US20140030330A1
2014/1/30
专利标题
:Dosage forms of apixaban
专利权人
:
BRISTOL-MYERS SQUIBB COMPANY
;
The present invention relates to a Factor Xa inhibitor dosage form comprising apixaban in a solubility-improved form wherein the dosage form provides controlled release of apixaban and methods for preventing or treating venous thromboembolisms deep vein thrombosis and acute coronary syndrome with said dosage form.
5.
US2014030330A1
2014/1/30
US201313933718
2013/7/2
专利标题
:DOSAGE FORMS OF APIXABAN
专利权人
:
SQUIBB BRISTOL MYERS CO [US]
;
PFIZER [US]
;
The present invention relates to a Factor Xa inhibitor dosage form comprising apixaban in a solubility-improved form wherein the dosage form provides controlled release of apixaban and methods for preventing or treating venous thromboembolisms, deep vein thrombosis and acute coronary syndrome with said dosage form.
6.
WO2013164839A8
2014/1/9
专利标题
:Amorphous form of apixaban, process of preparation and compositions thereof
专利权人
:
Cadila Healthcare Limited
;
The present invention discloses an amorphous form of apixaban process of preparation and compositions thereof.
7.
WO2013174498A1
2013/11/28
WO2013EP01461
2013/5/16
专利标题
:DOSAGE FORMS COMPRISING APIXABAN AND MATRIX FORMER
专利权人
:
RATIOPHARM GMBH [DE]
;
The invention relates to oral dosage forms for modified release of apixaban. The invention also relates to methods of preparing said dosage forms and to an agglomerated mixture of matrix former and filler for preparing an oral dosage form for use in the treatment of venous thromboembolism.
8.
WO2013164839A2
2013/11/7
WO2013IN00131
2013/3/5
专利标题
:AMORPHOUS FORM OF APIXABAN, PROCESS OF PREPARATION AND COMPOSITIONS THEREOF
专利权人
:
CADILA HEALTHCARE LTD
;
The present invention discloses an amorphous form of apixaban, process of preparation and compositions thereof.
9.
CN103360391A
2013/10/23
CN20131339561
2013/8/6
专利标题
:Novel apixaban crystal form and preparation method thereof
专利权人
:
QILU PHARMACEUTICAL CO LTD
;
10.
CN103342704A
2013/10/9
CN20131315775
2013/7/25
专利标题
:Preparation method of Apixaban as anti-thrombotic drug
专利权人
:
GANSU HAOTIAN CHEMEXPRESS CO LTD
;
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