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标题标题2专利权人发明人附图摘要摘要2优先权号IPC专利类型
首页12345下页尾页 共 48 条记录, 当前第1/5页。
公开号 公开日 申请号 申请日
1. CN102249998B 2013/9/25
专利标题：A kind of method for preparing along the phenylsulfonic acid atracurium 法律状态

2. US8461338B2 2013/6/11
专利标题：(1r, 1'r)-atracurium salts separation process 法律状态
专利权人：Chemagis Ltd.;
The present invention provides an improved method of chromatographically separating the isomers of (1RrR)-atracurium salts by high-performance liquid chromatography (HPLC) in the absence of a strong acid. The separation is preferably performed on a silica gel HPLC column using an eluent containing an organic solvent a polar aprotic co-solvent and a weak organic acid.

3. CN102898370A 2013/1/30 CN20121446799 2012/11/11
专利标题：Cis-atracurium besilate for injection 法律状态

4. US8357805B2 2013/1/22
专利标题：(1r,1′r)-atracurium salts separation process 法律状态
专利权人：Chemagis Ltd.;
The present invention provides an improved method for obtaining cisatracurium besylate which preferably chromatographically separating cisatracurium besylate from a mixture of (1R1′R)-atracurium isomers via flash chromatography.

5. US8354537B2 2013/1/15
专利标题：R,r1-atracurium salts 法律状态
专利权人：Chemagis Ltd.;
The present invention provides RR′-atracurium salts processes for producing and purifying such salts and methods of using such salts to produce highly pure cisatracurium besylate.

6. CN101337936B 2011/3/23
专利标题：A kind of method with column chromatography purifying phenylsulfonic acid atracurium 法律状态

7. CN101337935B 2011/1/12
专利标题：A kind of method with two-phase extraction method purifying phenylsulfonic acid atracurium 法律状态

8. CN101845017A 2010/9/29
专利标题：The atracurium besilate intermediates preparation 法律状态

9. US20100234602A1 2010/9/16
专利标题：Novel r,r`-atracurium salts 法律状态
专利权人：Chemagis Ltd.;
The present invention provides RR?-atracurium salts processes for producing and purifying such salts and methods of using such salts to produce highly pure cisatracurium besylate.

10. US20100174082A1 2010/7/8
专利标题：(1r,1'r)-atracurium salts separation process 法律状态
专利权人：Chemagis Ltd.;
The present invention provides an improved method for obtaining cisatracurium besylate which preferably chromatographically separating cisatracurium besylate from a mixture of (1R1?R)-atracurium isomers via flash chromatography


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