Provided herein, inter alia, are prodrugs of bimatoprost, methods of using the same and compositions including the same.

593376 Disclosed is a method of enhancing the growth of eyelashes in a person, comprising: opening a sterile sheath comprising a first sterile applicator brush and a second sterile applicator brush packaged together therein

The present invention is directed to compositions and methods comprising the use of bimatoprost and cyclosporine, used concurrently and in combination, to grow hair and for the treatment of all types of hair loss conditions such as but not limited toalopecia areata. The present invention is also directed to compositions containing bimatoprost and cyclosporine A to grow hair on the scalp and other areas of the body and methods of administration of the compositions.

An injectable composition or kit for treating hair loss includes biotin minerals and oligo-elements organic silicon pentoxyfilline and procaine hydrochloride. The minerals and oligo-elements include at least Boron (B) Sulfur (S). The composition can include a buffering agent for example sodium bicarbonate to maintain a desired pH for example a pH between about 5.3 and 5.7. The compositions can be used to promote hair loss caused by alopecia areata androgenic alopecia frontal fibrosing alopecia a...

Methods and compositions for stimulating the growth of hair are disclosed wherein said compositions include a cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl compound represented by the formula I wherein the dashed bonds represent a single or double bond which can be in the cis or trans configuration, A, B, Z, X, R1 and R2 are as defined in the specification. Such compositions are used in treating the skin or scalp of a human or non-human animal. Bimatoprost is preferred for this treatmen...

The present invention is directed to preservative-free solutions of bimatoprost for lowering intra-ocular pressure and treatment of glaucoma.

A convergent synthesis of the prostaglandin F2alpha analogues, travoprost and bimatoprost, was developed employing Julia-Lythgoe olefination of the structurally advanced phenylsulfone with an enantiomerically pure aldehyde omega-chain synthon. The novel convergent strategy allows the synthesis of a whole series of prostaglandin analogues of high purity from a common and structurally advanced prostaglandin intermediate.