A pharmaceutical composition comprises (a) an antibacterial agent in an antibacterially effective amount illustratively comprising clindamycin or a pharmaceutically acceptable salt or ester thereof; and (b) an antifungal agent in an antifungally effective amount illustratively comprising butoconazole or a pharmaceutically acceptable salt or ester thereof. The composition is adapted for application in a unit dose amount to a vulvovaginal surface and has at least one nonlipoidal internal phase and...

A pharmaceutical composition comprises (a) an antibacterial agent in an antibacterially effective amount, illustratively comprising clindamycin or a pharmaceutically acceptable salt or ester thereof

PURPOSE: A composition containing butoconazole is provided to prevent or treat neurodegenerative diseases, especially Alzheimer's disease. CONSTITUTION: A composition for preventing or treating neurodegenerative diseases contains butoconazole, a derivative thereof, or a pharmaceutically acceptable salt thereof. The neurodegerative diseases are selected from stroke, memory loss, memory injury, dementia, Parkinson's disease, Pick disease, Creutzfeld-Kacob disease, Huntingtun's disease, and amyotro...

FIELD: medicine pharmaceutics.SUBSTANCE: invention relates to medicine and pharmaceutical industry and concerns a combined pharmaceutical composition with antibacterial and antifungal activity. The composition comprises clindamycin phosphate butoconazole nitrate as active ingredients. As a basis the composition comprises a combination of a hydrophobic ingredient a hydrophilic ingredient and an emulsifier and a gelling agent. A method of preparing the declared composition involves that a solution...

A pharmaceutical composition comprises (a) an antibacterial agent in an antibacterially effective amount illustratively comprising clindamycin or a pharmaceutically acceptable salt or ester thereof; and (b) an antifungal agent in an antifungally effective amount illustratively comprising butoconazole or a pharmaceutically acceptable salt or ester thereof. The composition is adapted for application in a unit dose amount to a vulvovaginal surface and has at least one nonlipoidal internal phase and...

A pharmaceutical composition comprises (a) metronidazole in an antibacterially effective amount; and (b) an antifungal agent in an antifungally effective amount illustratively comprising butoconazole or a pharmaceutically acceptable salt or ester thereof.The composition is adapted for application in a unit dose amount to a vulvovaginal surface and has at least one nonlipoidal internal phase and at least one lipoidal external phase that is bioadhesive to the vulvovaginal surface.The composition i...