596057 Disclosed is a pharmaceutical composition comprising an anabolic steroid (such as oxymetholone oxandrolone nandrolone and esters thereof such as nandrolone decanoate) and a vitamin D compound (such as ergocalciferol cholecalciferol calcidiol calcitriol doxercalciferol or calcipotriene) in a carrier liquid wherein the composition is adapted for parenteral administration. Further disclosed is the use of an anabolic steroid and a vitamin D compound in the manufacture of a parenteral composit...

Bromoacetoxycalcidiol (B3CD), which is structurally related to calcidiol, exhibits cytotoxic and apoptotic activity toward cancer cells, including highly aggressive neuroblastoma cells. A series of small molecules designed around the structure of B3CD is expected to have growth inhibitory and apoptogenic activities toward a wide range of malignancies. B3CD shows no apparent toxicity in vivo, indicating potential value as a chemotherapeutic agent which will be particularly useful in treating high...