The present invention comprises a nanoparticulate composition comprising (a) a benzodiazepine having an effective average particle size of less than about 2000 nm wherein the benzodiazepine is selected from the group consisting of alprazolam brotizolam chlordiazepoxide clobazam clonazepam clorazepam demoxazepam flumazenil flurazepam halazepam midazolam nordazepam medazepam diazepam nitrazepam oxazepam midazepam prazepam quazepam triazolam temazepam loprazolam pharmaceutically acceptable salts an...

1. A pharmaceutical composition for the treatment of acute chronic and/or neuropathic pain and migraine comprising (a) a nicotine receptor partial agonist or a pharmaceutical acceptable salt thereof; (b) an analgesic agent or pharmaceutically acceptable salt thereof and (c) a pharmaceutical acceptable carrier; wherein the active agents "a" and "b" above are present in amounts that render the composition effective in treating acute chronic and/or neuropathic pain and migraine. 2. The pharmaceutic...

1457186 Therapeutic compositions HOECHST AG 22 Feb 1974 [24 Feb 1973] 8171/74 Heading A5B [Also in Division C2] Therapeutic compositions having hypolipaemic and (in some cases) hypoglycaemic activity and which are preferably administered orally comprise (with certain exclusions: see Division C2) compounds of formula wherein X is O or S; R1 is H C 1-6 alkyl or Ph; R2 is H or R1-R2 forms with the ring 4-C atom a carbocyclic 5- or 6-membered ring; R3 R4 R5 are each H halogen or NO 2 ; and R6 R7 a...

1305644 #-Adrenolytic medicines BOEHRINGER INGELHEIM GmbH 16 April 1970 [16 April 1969] 18243/70 Heading A5B Pharmaceutical compositions having improved #-adrenolytic activity comprise a #- receptor blocking agent of the 1-aryloxy-2- hydroxy-3-aminopropane or 1-aryl-1-hydroxy- 2-amino-methane type and a "minor tranquilizer". The #-adrenolyties are those of the general formula: Ar-OCH 2 -CHOH-CH 2 - NHR wherein Ar is an iso- homo- or heterocyclic group which contains at least one 6- membered arom...

1243991. CNS depressants. IMPERIAL CHEMICAL INDUSTRIES Ltd. 4 Sept. 1969 [10 June 1968] No. 27501/68. Heading A5B. [Also in Division C2] Pharmaceutical compositions suitable for oral or parenteral administration and having depressant activity on the central nervous system and thymoleptic activity contain novel piperidine piperazine or morpholine derivatives of the formula wherein A is -O- -CH 2 - or =NCOR where R is H alkyl aryl halogenoaryl alkoxy aryloxy arolkloxy or amino and X is phenyl whi...

A water-dispersible veterinary preparation comprises (a) up to 50% by weight of a therapeutically active substance (b) from 2 to 70% by weight of a polyethyleneglycol which is solid at room temperature and (c) from 10 to 70% by weight of an amphiphilic agent which is solid at room temperature the preparation being in the form of particles the major portion of which have a diameter within the range of 50-200m . The polyethyleneglycol may have an average molecular weight of 2000-10000. The amphi...

A water-dispersible veterinary preparation comprises (a) up to 50% by weight of a therapeutically active substance (b) from 2 to 70% by weight of a polyethyleneglycol which is solid at room temperature and (c) from 10 to 70% by weight of an amphiphilic agent which is solid at room temperature the preparation being in the form of particles the major portion of which have a diameter within the range of 50-200m . The polyethyleneglycol may have an average molecular weight of 2000-10000. The amphi...