The present invention relates to compounds useful as inhibitors of choline kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.

The present invention relates to compounds useful as inhibitors of choline kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.

The invention relates to medicine specifically to dentistry and concerns medicinal agents for the prophylaxis and treatment of infectious and inflammatory periodontal diseases particularly medicinal agents for the prophylaxis and treatment of periodontosis. Essence of the invention: A pharmaceutical composition in the form of a gel for the prophylaxis and treatment of periodontal diseases containing metronidazole benzoate and chlorhexidine gluconate as the active agent carbomer and hydroxypropyl...

The present invention relates to compositions and methods for treatment of depression anxiety schizophrenia sleep disorder or epilepsy comprising monocholine salt of succinic acid of a formula (I) or a pharmaceutically acceptable salt thereof. Preferably the pharmaceutically acceptable salt is dicholine salt of succinic acid of a formula (II).

A compound represented by the structure of the general formula (A): L- Z-Y-- X -~- n 5 (A) wherein L is a lipid or a phospholipid

A preparation is disclosed for producing enhanced blood flow in tissue thus causing beneficial effects such as promoting hair growth on scalp tissuelacking sufficient hair, restoring normal sexual function in males with erectile dysfunction. Specifically, this is a preparation which provides local delivery of the amino acid L-arginine, an important biological precursor to the main substance which is responsible for relaxation of blood vessels permitting enhancement of blood flow. In the preferre...

A preparation is disclosed for producing enhanced blood flow in tissue thus causing beneficial effects such as promoting hair growth on scalp tissue lacking sufficient hair, restoring normal sexual function in males with erectile dysfunction. Specifically, this is a preparation which provides local delivery of the amino acid L-arginine, an important biological precursor to the main substance which is responsible for relaxation of blood vessels permitting enhancement of blood flow. In the preferr...

The invention relates to a composition comprising: i) one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof

The present invention relates to a method for separating polypeptides or proteins tagged with histidine glues from a mixture of proteins (for example, a cell extract), by means of a system of two aqueous phases in which one of the components is PEG, and in which the protein tagged with polyhistidine is preferably distributed in the PEG-rich phase under specific conditions. The purification process can include one or more washing steps and is completed with an inversion in the distribution of the...