The invention concerns the use of an H1- and/or H2-histamine receptor antagonist for the reduction of intracranial pressure (ICP) in particular for the prevention and treatment of elevated intracranial pressure and/or secondary ischaemia in particular caused by brain injury more in particular caused by traumatic (TBI) and non-traumatic brain injury. In particular the histamine antagonist is selected from the group of acrivastine alimemazine antazoline astemizole azatadine azelastine brompheniram...

The invention includes compositions for transmucosal administration to an animal comprising at least one active agent and a pharmaceutically acceptable carrier. A preferred active agent is selected from the group consisting of meloxicam carprofen enrofloxacin clemastine diphenhydramine digoxin levothyroxine cyclosporine ondansetron lysine zolpidem propofol nitenpyram ivermectin milbemycin and pharmaceutically acceptable salts solvates and esters thereof. In another embodiment the invention inclu...

PROBLEM TO BE SOLVED: To provide a composition comprising at least one activator and a pharmaceutically acceptable carrier which is to be administered transmucosally to an animal. SOLUTION: A preferable activator is selected from a group of meloxicam caprofen enrofloxacin clemastine diphenhydramine digoxin levothyroxine cyclosporine ondansetron lysine zolpidem propofol nitenpyram ivermectin milbemycin and their pharmaceutically acceptable salts solvates and esters thereof. Also provided is a me...

PROBLEM TO BE SOLVED: To provide a phermaceutical composition superior in storage stability, which contains loxoprofen or its salt, codeine, etc.

The invention relates to medicine namely to creation of medicinal composition in the form of gel for external application having an antiinflammatory and antiallergic effect which can be widely used as a first aid means for treating antiinflammatory and antiallergic skin diseases burn of I-II degrees blood-sucking insects itching bruises scratches contusions etc for treating vasomotor and allergic rhinitis as well as inflammatory diseases of eyes with allergic manifestations. Gel possessing antii...

PROBLEM TO BE SOLVED: To provide a pharmaceutical composition which has excellent storage stability, and contains loxoprofen or a salt thereof and carbinoxamine or a salt thereof, and the like.

The invention includes compositions for transmucosal administration to an animal comprising at least one active agent and a pharmaceutically acceptable carrier. A preferred active agent is selected from the group consisting of meloxicam carprofen enrofloxacin clemastine diphenhydramine digoxin levothyroxine cyclosporine ondansetron lysine zolpidem propofol nitenpyram ivermectin milbemycin and pharmaceutically acceptable salts solvates and esters thereof. In another embodiment the invention inclu...