The present invention relates to stable topical pharmaceutical compositions for the treatment of psoriasis. Disclosed are in particular nonoemulsions comprising nano size droplets of one or more anti-psoriasis agents, e.g. clobetasol and/or salicylic acid. These compositions exhibit greater permeability, and improved bioavailability. The invention also relates to processes for the preparation of such compositions.

The present invention relates to stable topical pharmaceutical compositions for the treatment of psoriasis. Disclosed are in particular nonoemulsions comprising nano size droplets of one or more anti -psoriasis agents, e.g. clobetasol and/or salicylic acid. These compositions exhibit greater permeability, and improved bioavailability. The invention also relates to processes for the preparation of such compositions.

The present invention is related to skin creams in general, and specifically to a cream composition for skin depigmentation acting as a topical melanin reducing agent for the treatment of hyperchromia, chloasma and acne, which gradually reduces the hyperpigmentation of skin and acne in a short term showing satisfactory results without side effects. The inventive composition is characterized in that it comprises tretinoine, clobetasol propionate, hydroquinone, and an excipient with or without a s...