The present invention is concerned with an anthelmintic paste in form of an aqueous suspension comprising a veterinarily effective amount each of praziquantel and a macrocyclic lactone selected from avermectins milbemycins and derivatives thereof; a cyclodextrin; a thickener; and water. The suspension formulations of the present invention are useful for controlling endoparasites in warm-blooded animals such as companion animals.

The present invention relates to improvements in the oral formulations of the anthelmintic praziquantel used for control and treatment of endoparasitic infestations in warm-blooded animals in particular in companion animals such as cats, dogs and horses and methods of producing the formulations. The composition of the invention comprises particles of praziquantel with an integral coating of a lipid or a mixture of lipids which are insoluble in water and which serve to mask to extremely bitter ta...