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[药品] 包含 'Ursodeoxycholic acid'
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公开号
公开日
申请号
申请日
1.
WO2014020024A1
2014/2/6
WO2013EP66002
2013/7/30
专利标题
:PROCESS FOR PREPARING HIGH PURITY URSODEOXYCHOLIC ACID
专利权人
:
ERREGIERRE SPA [IT]
;
The present invention describes a process for the synthesis of ursodeoxycholic acid wherein the purification of the crude ursodeoxycholic acid (containing approximately 13-15% of chenodeoxycholic acid impurity) takes place first passing through a salification with imidazole and a subsequent purification via "methyl ester", which allows a finished product with an extremely low content of known "cheno and "litho" impurities to be obtained. The present invention also describes the recovery steps of...
2.
US2014011786A1
2014/1/9
US201314017857
2013/9/4
专利标题
:SYNTHESIS AND USE OF ANTI-TUMOR DRUG LQC-Y
专利权人
:
LEI HAIMIN [CN]
;
Disclosed are the general structural formula of LQC-Y as well as the synthesis and use thereof. Pharmacological experiments demonstrated the marked antitumor effect of such compounds. Single day administration of LQC-Y3 to mice at a maximum dose of 6000 mg/kg showed no toxicity response during the 14-day continuous observation period, indicating the high safety of the compounds, and the compounds can be used to prepare medicaments for preventing and treating carcinomas such as liver cancer, lung...
3.
WO2013180253A1
2013/12/5
WO2013JP65126
2013/5/24
专利标题
:pH-SENSITIVE CARRIER AND METHOD FOR PRODUCTION THEREOF, pH-SENSITIVE MEDICINE AND pH-SENSITIVE PHARMACEUTICAL COMPOSITION EACH CONTAINING SAID CARRIER, AND CULTURE METHOD USING SAID pH-SENSITIVE MEDICINE OR SAID pH-SENSITIVE PHARMACEUTICAL COMPOSITION
专利权人
:
TERUMO CORP [JP]
;
Provided are: a pH-sensitive carrier which can be used as a carrier for a physiologically active substance and can respond to a weakly acidic environment to exhibit an effect of promoting a membrane-disrupting function
4.
US2013323320A1
2013/12/5
US201313907301
2013/5/31
专利标题
:pH SENSITIVE CARRIER AND PREPARATION METHOD THEREOF, AND pH SENSITIVE DRUG AND pH SENSITIVE DRUG COMPOSITION EACH CONTAINING THE CARRIER, AND METHOD FOR TREATING OR PREVENTING DISEASES USING THE SAME
专利权人
:
TERUMO CORP [JP]
;
A pH sensitive carrier which includes at least one pH sensitive compound selected from the group consisting of deoxycholic acid, cholic acid, ursodeoxycholic acid, chenodeoxycholic acid, hyodeoxycholic acid, C27 bile acid, glycodeoxycholic acid, glycyrrhizic acid, glycyrrhetinic acid and salts thereof, and at least one amphipathic substance selected from the group consisting of a phosphatidylcholine having 10 to 12 carbon atoms, a polyoxyethylene sorbitan monofatty acid ester having 12 to 18 car...
5.
CN101781350B
2013/11/20
专利标题
:Method for purifying ursodeoxycholic acid by mixed solvent
专利权人
:
Zhejiang University
;
6.
CN103385880A
2013/11/13
CN20131286061
2013/7/9
专利标题
:Ursodeoxycholic acid vitamin composition, preparation method and applications thereof
专利权人
:
WORLDCO INTERNAT CO LTD
;
7.
CN103319560A
2013/9/25
CN2013102127
2013/1/4
专利标题
:Preparation method of ursodeoxycholic acid
专利权人
:
UNIV EAST CHINA SCIENCE & TECH
;
8.
RU2490018C1
2013/8/20
RU20120128045
2012/7/3
专利标题
:METHOD OF DOG'S HEPATOSIS THERAPY
专利权人
:
FEDERAL NOE G BJUDZHETNOE OBRAZOVATEL NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL NOGO OBRAZOVANIJA TJUME [RU]
;
FIELD: medicine.SUBSTANCE: invention refers to veterinary science, and may be used for dog's hepatosis therapy. The method for dog's hepatosis therapy involves using a hepatoprotector, a microelement and herbal tea
9.
RU2490017C1
2013/8/20
RU20120131593
2012/7/23
专利标题
:METHOD OF CONSERVATIVE TREATMENT OF LITHIC STAGE OF CHOLELITHIASIS
专利权人
:
G BJUDZHETNOE OBRAZOVATEL NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL NOGO OBRAZOVANIJA IZHEV GMA MIN ZDR [RU]
;
GORBUNOV ALEKSANDR JUR EVICH [RU]
;
FIELD: medicine.SUBSTANCE: invention refers to medicine, particularly gastroenterology, and may be used for treating the lithic stage of cholelithiasis. For this purpose, ursodeoxycholic acid is administered for the night with underlying the mineral water Uvinskaya heated to 40-45 DEG C.EFFECT: method enables increasing the clinical effectiveness ensured by reducing high lithogenicity of bile with improved gallbladder contractility.2 cl, 1 tbl, 2 ex
10.
CN103183716A
2013/7/3
专利标题
:A kind of preparation method of ursodeoxycholic acid
专利权人
:
Shandong Tianlv Pharmaceutical Co.,ltd.
;
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