Compositions, and methods of using such compositions, useful for injection into the posterior segments of human or animal eyes are provided. Such compositions include small particles of a poorly soluble therapeutic agent that facilitates formation of concentrated regions of the therapeutic agent in the retinal pigmented epithelium of an eye. The particles are formed by combining a therapeutic agent with an ophthalmically acceptable polymer component. The particles have sizes less than about 3000...

The present invention is drawn to formulations and related methods for treating dermatitis or psoriasis. The formulation can include triamcinolone acetonide, a polymer selected from the group of a poly(2-hydroxyalkylacrylate), a poly(2-hydroxyalkylmethacrylate), and combinations thereof. The formulation also includes a volatile solvent system including at least one volatile solvent, and a non-volatile solvent system including at least one non-volatile solvent.

The present invention is drawn to formulations and related methods for treating dermatitis or psoriasis. The formulation can include triamcinolone acetonide a polymer selected from the group of a poly(2-hydroxyalkylacrylate) a poly(2-hydroxyalkylmethacrylate) and combinations thereof. The formulation also includes a volatile solvent system including at least one volatile solvent and a non-volatile solvent system including at least one non-volatile solvent.

The present invention further provides method of preparing nanocrystals of a hydrophobic therapeutic agent such as fluticasone or triamcinolone, pharmaceutical compositions (e.g., topical or intranasal compositions) thereof and methods for treating and/or preventing the signs and/or symptoms of disorders such as blepharitis, meibomian gland dysfunction or skin inflammation or a respiratory disease (e.g., asthma).

The invention relates to nitrooxy derivatives of fluocinolone acetonide, triamcinolone acetonide, betamethasone and beclomethasone, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating diabetic macular edema, diabetic retinopathy, macular degeneration, age-related macular degeneration and other diseases of retina and macula lutea.

An injectable composition or kit for treating hair loss includes biotin minerals and oligo-elements organic silicon pentoxyfilline and procaine hydrochloride. The minerals and oligo-elements include at least Boron (B) Sulfur (S). The composition can include a buffering agent for example sodium bicarbonate to maintain a desired pH for example a pH between about 5.3 and 5.7. The compositions can be used to promote hair loss caused by alopecia areata androgenic alopecia frontal fibrosing alopecia a...

[Problem] The purpose of the present invention is to provide a neuroprotective agent which is capable of effectively protecting intraocular cells including optic nerves and is effective as a composition for ophthalmic membrane staining in cases where removal of an ophthalmic membrane is carried out. [Solution] The purpose is achieved by a neuroprotective agent which contains, as active ingredients: Brilliant Blue G, a pharmaceutically acceptable salt thereof or a harmaceutically acceptable solva...