The invention is directed to improved methods for modulating the human sexual response by administering a vasodilator selected from the group consisting of phentolamine phentolamine mesylate phentolamine hydrochloride apomorphine phenoxybenzamine nitroglycerin thymoxamine nicotinyl alcohol imipramine verapamil isoxsuprine naftidrofuryl tolazoline and papaverine to the circulation through transmucosal including but not limited to administration through the vaginal mucosa transdermal intranasal or...

The invention is directed to improved methods for modulating the human sexual response by administering a vasodilator selected from the group consisting of phentolamine phentolamine mesylate phentolamine hydrochloride apomorphine phenoxybenzamine nitroglycerin thymoxamine nicotinyl alcohol imipramine verapamil isoxsuprine naftidrofuryl tolazoline and papaverine to the circulation through transmucosal including but not limited to administration through the vaginal mucosa transdermal intranasal or...

Dipeptides and amino acids of the formula A-E-G are disclosed wherein A is e.g. hydrogen or a- RbCO or RbSO2- where Ra and Rb are e.g. alkyl cycloalkyl or aryl;whereinR' is e.g. alkyl;n is 0 1;R2 is e.g. hydrogen or alkyl;R3 is OH NH2are e.g. alkyl;R4 is e.g. hydrogen or alkylR6 is H or methyl;R7 is e.g. hydrogen or alkyl;R8 is e.g. hydrogen methyl or cycloalkyl such that when R8 is cycloalkyl R6 and R7 are hydrogen;R9 is e.g. hydroxy.The compounds have enzyme inhibitor activity e.g. renin inhib...