The invention provides pharmaceutical compositions for topical administration in treating vaginal infections e.g. vaginitis. Such compositions comprise: W at least one triazole compound active against Candida albicans preferably at least one such compound which is additionally active against one or more non- albicans Candida species and (ii) at least one additional anti-vaginitis medicament preferably an anti-fungal anti-protozoal and/or anti-bacterial agent. Preferred compositions include as ac...

An aqueous terconazole composition comprises at least about 0.4 percent by weight of terconazole dissolved in water and a terconazole crystallization-inhibiting amount of an organic acid. Preferably the organic acid is a water soluble alkyl carboxylic acid a polybasic organic acid or a combination thereof. The composition is free from terconazole crystals at an ambient temperature of about 20° C. Methods of preparing the composition are also described. The compositions provide for improved thera...

An aqueous tinidazole and terconazole composition comprises at least about 0.5 percent by weight of tinidazole and about 0.4 to about 3 percent by weight of terconazole dissolved in water and a crystallization-inhibiting amount of an organic acid. Preferably the organic acid is citric acid. The composition is free from crystals at an ambient temperature of about 20° C. Methods of preparing the composition are also described.

This invention relates to a method of treating otitis externa using a topical combination medication including one or more antifungal agent such as for example fluconazole voriconazole itraconazole clotrimazole amphotericin B caspofungin micafungin terbinafine naftifine butenafine amorolfine ravuconazole posaconazole flucytosine econazole enilaconazole miconazole oxiconazole saperconazole sulconazole terconazole tioconazole nikkomycin Z anidulafungin (LY303366) nystatin pimaricin griseofulvin ci...

This invention relates to a method of treating otitis externa using a topical combination medication including one or more antifungal agent such as for example fluconazole voriconazole itraconazole clotrimazole amphotericin B caspofungin micafungin terbinafine naftifine butenafine amorolfine ravuconazole posaconazole flucytosine econazole enilaconazole miconazole oxiconazole saperconazole sulconazole terconazole tioconazole nikkomycin Z anidulafungin (LY303366) nystatin pimaricin griseofulvin ci...

This invention relates to a method of treating otitis externa and in particular otitis externa of fungal etiology using topical medication including antifungal agents such as for example fluconazole voriconazole itraconazole clotrimazole amphotericin B caspofungin (Cancidas®) micafungin (Mycamine®) terbinafine naftifine butenafine amorolfine ravuconazole posaconazole flucytosine econazole enilaconazole miconazole oxiconazole saperconazole sulconazole terconazole tioconazole nikkomycin Z an...

This invention relates to a method of treating otitis externa using a topical combination medication including one or more antifungal agent such as for example fluconazole voriconazole itraconazole clotrimazole amphotericin B caspofungin micafungin terbinafine naftifine butenafine amorolfine ravuconazole posaconazole flucytosine econazole enilaconazole miconazole oxiconazole saperconazole sulconazole terconazole tioconazole nikkomycin Z anidulafungin (LY303366) nystatin pimaricin griseofulvin ci...

This invention relates to a method of treating otitis externa and in particular otitis externa of fungal etiology using topical medication including antifungal agents such as for example fluconazole voriconazole itraconazole clotrimazole amphotericin B caspofungin (Cancidas®) micafungin (Mycamine®) terbinafine naftifine butenafine amorolfine ravuconazole posaconazole flucytosine econazole enilaconazole miconazole oxiconazole saperconazole sulconazole terconazole tioconazole nikkomycin Z anidulaf...

This invention relates to a method of treating otitis externa using a topical combination medication including one or more antifungal agent such as for example fluconazole voriconazole itraconazole clotrimazole amphotericin B caspofungin micafungin terbinafine naftifine butenafine amorolfine ravuconazole posaconazole flucytosine econazole enilaconazole miconazole oxiconazole saperconazole sulconazole terconazole tioconazole nikkomycin Z anidulafungin (LY303366) nystatin pimaricin griseofulvin ci...