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[药品] 包含 'Tamoxifen'
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公开号
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申请号
申请日
1.
WO2014023791A1
2014/2/13
WO2013EP66595
2013/8/7
专利标题
:TREATMENT OF DRUG RESISTANCE IN HORMONE-SENSITIVE CANCER
专利权人
:
PELICAN HEALTH LTD [GB]
;
The present invention provides an ex vivo method for determining whether tumour cells in a patient are, or are likely to become, resistant to a drug that modulates the binding of a steroid hormone to its receptor, comprising: (i) determining the expression level of one or more of the miRNAs listed in Table and/or Table 2 in a biological sample from the patient
2.
EP2695942A1
2014/2/12
EP20120179587
2012/8/7
专利标题
:microRNAs in therapy and diagnostic of cancer
专利权人
:
PELICAN HEALTH LTD [GB]
;
The present invention provides an ex vivo method for determining whether tumour cells in a patient are, or are likely to become, resistant to a drug that modulates the binding of a steroid hormone to its receptor, comprising: (i) determining the expression level of one or more of the miRNAs listed in Table 1 and/or Table 2 in a tumour cell sample obtained from the patient
3.
CN103554116A
2014/2/5
专利标题
:A kind of molecular targeted anticancer photosensitizer tamoxifen-phthalocyanine conjugates and preparation method thereof
专利权人
:
4.
WO2014008159A1
2014/1/9
WO2013US48872
2013/7/1
专利标题
:SELECTIVE ESTROGEN RECEPTOR DEGRADERS FOR TREATMENT OF TAMOXIFEN RESISTANT TUMORS
专利权人
:
UNIV NORTH CAROLINA [US]
;
NOVOLIPID INC [US]
;
Compositions and methods for covalently bonding a polycarboxylic fatty acid and a SERD (selective estrogen receptor degrader) to form fatty acid-drug conjugate compounds are described. The conjugate compounds are useful for increasing solubility of the SERD as well as targeting the SERD to solid tumors. In particular, the compounds are surprisingly efficacious against tamoxifen-resistant tumors. These types of tumors are recalcitrant to existing therapies and often signal the end stage of cancer...
5.
CN103494776A
2014/1/8
专利标题
:The tamoxifen citrate freeze-dried powder
专利权人
:
6.
CN103494787A
2014/1/8
专利标题
:The tamoxifen citrate drop pill
专利权人
:
7.
EP1941871B1
2014/1/8
专利标题
:Formulations for prevention and treatment of breast cancer with 4-hydroxy tamoxifen
专利权人
:
BESINS HEALTHCARE LUXEMBOURG SARL
;
8.
CA2775266C
2013/12/31
专利标题
:Anti-cancer tamoxifen-melatonin hybrid ligand
专利权人
:
Duquesne University Of The Holy Spirit, A Nonprofit Corporation Organized Under The Laws Of The Commonwealth Of Pennsylvania
;
A particularly constructed tamoxifen-melatonin hybrid ligand gives new and unexpectedly improved results in the prevention and treatment of cancer particularly breast cancer. The hybrid ligand comprises either tamoxifen or 4-hydroxytamoxifen and also melatonin with the tamoxifen or 4-hydroxytamoxifen and melatonin's being linked by an unsubstituted C2-C6 alkyl linker between the tamoxifen amine and the carbonyl of melatonin.
9.
CN103450036A
2013/12/18
CN20131357673
2013/8/15
专利标题
:Preparation method of high-purity tamoxifen citrate
专利权人
:
ASYMCHEM LAB TIANJIN CO LTD
;
ASYMECHEM LIFE SCIENCE TECHNOLOGY TIANJIN CO LTD
;
ASYCHEM PHARMACEUTICALS TIANJIN CO LTD
;
ASYMCHEM MEDICAL CHEMICAL FUXIN TECHNOLOGY CO LTD
;
ASYMCHEM LAB JILIN CO LTD
;
10.
CN103393638A
2013/11/20
CN20131299725
2013/7/17
专利标题
:Application of formononetin in preparing medicine for treating breast cancer
专利权人
:
GUILIN MEDICAL UNIVERSITY
;
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