Controlling exogenous polyamines may be used, in some aspects, as an adjunctive strategy to chemoprevention with polyamine inhibitory agents, for example, anti-carcinoma combination therapies comprising ornithine decarboxylase (ODC) inhibitor and a spermidine/spermine N1-acetyltransferase expression agonist, optionally based on a patient's ODC1 promoter genotype. Assessing a tissue polyamine level or tissue polyamine flux may be used in some aspects, for predicting the efficacy of an anti-carcin...

Water-based drilling mud lubricants using a blend of fatty acid polyamine salts and fatty acid esters give synergistically better lubricity results than either component used separately. For example, the blends with different ratios of fatty acid diethylenetriamine salt and fatty acid methyl ester demonstrate much better lubricity in water-based drilling fluids than those where only fatty acid diethylene-triamine salt or fatty acid methyl ester are separately used. The amines in fatty acid amine...

PURPOSE: A carbon dioxide absorber containing biogenic amines and a method for removing carbon dioxide from exhaust gas using the same are provided to improve environmentally-friendly property and carbon dioxide absorbing rate and speed and to save the cost required to perform operational processes. CONSTITUTION: A carbon dioxide absorber contains a biogenic amine aqueous solution. Biogenic amines are prepared by the decarboxylation of free amino acids by a biological or chemical catalyst. The b...

The present invention relates to inhibitors of SSAT or AMD for the prevention or treatment of rheumatoid arthritis. 4-[(2E)-2-(4-carbamimidoylphenyl)iminohydrazino]-benzamidine (Diminazen) is preferred.

The invention provides new lipopolyamines of spermine type of the general formula I, wherein X is C-N bond or aminopolyethyleneglycolcarboxamide linker or o-hydroxy- alkylcarboxamide linker or omega-hydroxyalkylcarboxamidopolyethyleneglycol- carboxamide linker, and wherein a hydrophobic domain Y is an acyl symmetrically branched in the position C(2) or cholesteryl. The invention further provides a method of preparation of said lipopolyamines and their use for construction of polycationic liposom...

The present invention relates to novel compositions including a mixture of cadaverine, putrescine, spermine and spermidine at a concentration varying from 0.31 to 0.63 nmol per gram of composition, said composition also including agmatine at a concentration varying from 120 to 17,100 nmols per gram of composition, and to the uses thereof in treating diseases associated with the hyperproliferation of cells in a patient.

The present invention relates to a method of increasing the thermal hysteresis activity exhibited by a composition containing an antifreeze protein and water, wherein the method includes incorporating the antifreeze protein and any one or more substances selected from the following additive group A into the water. According to the present invention, the method of further increasing the thermal hysteresis activity inherently possessed by an antifreeze protein can be provided. Additive group A: an...

This invention relates to the use of a preparation comprising sulfated oligosaccharides which trap spermine and/or spermidine, as an active slimming ingredient in a cosmetic, pharmaceutical and/or nutraceutical composition. One aspect of the invention is to supply a cosmetic, pharmaceutical or nutriceutical composition with a slimming effect.

The present invention relates to inhibitors of SSAT or AMD for the prevention or treatment of rheumatoid arthritis. 4-[(2E)-2-(4-carbamimidoylphenyl)iminohydrazino]-benzamidine (Diminazen) is preferred.