The invention provides a novel process for the synthesis of 2-(2-hydroxyphenyl)-benz[1,3]oxazin-4-one, the process comprising of reacting the salicylic acid with salicylamide in the presence of p-toluenesulfonyl chloride, base and solvent. The use of 2-(2-hydroxyphenyl)-benz[1,3]oxazin-4-one in the preparation of Deferasirox is also disclosed in the invention.

The application discloses compounds of Formula I: wherein Q1 Q2 R1 R2 R3 and n are defined as described herein. Also provided are pharmaceutical compositions methods of using and methods of preparing the subject compounds.