The present invention is directed to a process for the preparation of the compound of Formula (I) comprising the step of converting a compound selected from the group consisting of the compounds of formulae (II) (III) and (IV) wherein X is halogen in one or more steps to give the compound of formula (I). The invention is also directed to a process for the preparation of a pharmaceutical composition comprising the compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof. M...

The present invention provides a method for preparing a film comprising a high amount of a sildenafil free base uniformly dispersed therein and having a suitable thickness and size, as well as flexibility providing good handling stability and being not prone to breaking. The present invention also provides a sildenafil free base-containing film prepared from the method.

The present invention provides a method for preparing a film comprising a high amount of a sildenafil free base uniformly dispersed therein and having a suitable thickness and size, as well as flexibility providing good handling stability and being not prone to breaking. The present invention also provides a sildenafil free base-containing film prepared from the method.

The present invention provides a method for preparing a film comprising a high amount of a sildenafil free base uniformly dispersed therein and having a suitable thickness and size as well as flexibility providing good handling stability and being not prone to breaking. The present invention also provides a sildenafil free base-containing film prepared from the method.

The present invention relates to medicine in particular to pharmaceutical industry and provides a tablet for the treatment of male erectile dysfunction comprising sildenafil or a pharmaceutically acceptable salt thereof as an active substance. The tablet also comprises hydroxypropylcellulose and colloid anhydrous silicon dioxide and film-coated. The invention also provides a method for manufacturing the tablet and use thereof for the treatment of male erectile dysfunction. According to the inven...

Provided is a fast dissolving film composition comprising a medically active component as an active ingredient in which the bitter taste of the active ingredient is masked and the fast dissolving film composition has a high content of 50% or higher. More particularly provided is a pharmaceutical composition which comprises sildenafil or pharmaceutically acceptable salts thereof as an active ingredient and which comprises a combination of a specific bitter taste masking agent to achieve masking o...