PURPOSE: A composition comprising an agonist or an antagonist of dopamine D2 receptor is provided to control the activity of Nurr1 and the development of neuron to treat diseases related to the activity of the Nurr1 and to simply screen a test compound or a clinical drug having the effect on the diseases related to the activity of the Nurr1.CONSTITUTION: A composition for controlling the activity of Nurr1 or the development of neuron comprises an agonist or an antagonist of dopamine D2 receptor ...