PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for improving goblet cell hyperplasia suppressing action containing fudosteine and an anticholinergic agent.SOLUTION: The pharmaceutical composition contains fudosteine in combination with an anticholinergic agent such as belladonna total-alkaloid isopropamide atropine scopolamine scopolia extract isopropamide propantheline and piperidolate. The composition suppresses the formation of goblet cells of the airway and the antitussive and...

Anticholinergic drugs in the form of parenteral therapeutic systems which release these drugs continuously are used for the treatment of hyperacidity and peptic ulcers.The anticholinergic drug may be utropine homatropine scopolamine benzatropine etybenzatropine oxyphencyclimine glycopyrrolate poldine propantheline isopropamide or clidinium.The therapeutic system is preferably a transdermal skin patch/plaster.Antacids and/or H2- receptor-antagonists e.g. cimetidine ranitidine metiamide burimamide...

Compositions comprising medazepam and propantheline halide useful in treating gastrointestinal disorders are disclosed.