The present invention comprises a nanoparticulate composition comprising (a) a benzodiazepine having an effective average particle size of less than about 2000 nm wherein the benzodiazepine is selected from the group consisting of alprazolam brotizolam chlordiazepoxide clobazam clonazepam clorazepam demoxazepam flumazenil flurazepam halazepam midazolam nordazepam medazepam diazepam nitrazepam oxazepam midazepam prazepam quazepam triazolam temazepam loprazolam pharmaceutically acceptable salts an...