The present invention relates to improved microparticles comprising a somatostatin analogue a process of making said microparticles and to pharmaceutical compositions comprising the same.

Present invention relates to new fields of application of pasireotide, in particular for the treatment high blood pressure and/or high cortisol levels, the new fields being obesity, depression, stress and/or alcoholism.

The present invention relates to a pharmaceutical composition of an extended release thereof comprising improved microparticles with a polymer matrix comprising pasireotide pamoat as an active component and a method of treating using said composition. A process is also described of making microparticles and a kit comprising said microparticles.