专利信息

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专利标题：Isolated isomers of norelgestromin and methods of making and using the same

The invention is directed to a process of preparing substantially pure d-(17?)-13-ethyl-17-hydroxy-1819-dinorpregn-4-ene-20-yn-3-one-3E- and -3Z-oxime isomers as well as a process for the synthesis of the mixture of isomers and the pure isomers. The invention also relates to substantially pure d-(17?)-13-ethyl-17-hydroxy-1819-dinorpregn-4-ene20-yn-3-one-3E-oxime and substantially pure d-(17?)-13-ethyl-17-hydroxy-1819-dinorpregn-4-ene-20-yn-3-one-3Z-oxime isomer. Further aspects of the invention ...

专利标题：Process of making isomers of norelgestromin and methods using the same

The invention is directed to a process of preparing substantially pure d-(17α)-13-ethyl-17-hydroxy-1819-dinorpregn-4-ene-20-yn-3-one-3E- and -3Z-oxime isomers as well as a process for the synthesis of the mixture of isomers and the pure isomers. The invention also relates to substantially pure d-(17α)-13-ethyl-17-hydroxy-1819-dinorpregn-4-ene20-yn-3-one-3E-oxime and substantially pure d-(17α)-13-ethyl-17-hydroxy-1819-dinorpregn-4-ene-20-yn-3-one-3Z-oxime isomer. Further aspects...

专利标题：Transdermal therapeutic system comprising norelgestromin for contraception and hormone replacement

专利标题：Transdermales therapeutisches system enthaltend norelgestromin zur kontrazeption und hormonsubstitution

Transdermal patch for administering norelgestromin comprises a drug-impermeable backing layer and a matrix layer comprising norelgestromin a silicone and diethylene glycol monoethyl ether butanediol or propylene glycol. - ACTIVITY None given. - MECHANISM OF ACTION Progestin.

专利标题：Matrix-controlled transdermal therapeutic system based on an adhesive for administering norelgestromin or the combination thereof with an estrogen

专利权人：HEXAL AG;

The invention relates to a transdermal therapeutic system comprising an active-ingredient-impermeable top layer an active-ingredient-containing matrix and a removable protective layer the matrix comprising or consisting of norelgestromin and an optional oestrogen as active ingredients as well as also a pressure-sensitive hot-melt adhesive and optional auxiliaries.

专利标题：Process for the preparation of norelgestromin

专利权人：Sterling Srl;

Process for the preparation of Norelgestromin or 17α-hydroxy-13β-ethyl-1819-dinorpregn-4-ene-20-yn-3-one oxime also in crystalline form in particular with an E/Z isomer ratio of between 1.3 and 1.5.

专利标题：Transdermal therapeutic system comprising norelgestromin for contraception and hormone replacement

The present invention relates to a transdermal therapeutic system for applying the active ingredient norelgestromin onto the skin optionally in combination with estrogens. It further relates to the use of such systems for hormonal contraception and for hormone replacement therapy.

专利标题：Transdermal therapeutic system comprising norelgestromin for contraception and hormone replacement

专利标题：Transdermal therapeutic system comprising norelgestromin forcontraception and hormone replacement

专利标题：Transdermal patch for administering norelgestromin has a matrix layer comprising norelgestromin, a silicone and diethylene glycol monoethyl ether, butanediol or propylene glycol

当前查询条件: [药品] 包含 'Norelgestromin'

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!	专利类型	发明实用新型外观设计
!	公开号			CN1234
!	申请号			CN1234
!	专利标题		扩展	PHARMA
!	专利权人		扩展	pfizer
	发明人
!	申请日			yyyymmdd
!	公开日			yyyymmdd
	优先权号
!	摘要		扩展	PHARMA
	IPC			A01B

	1. US20090312299A1	2009/12/17
	专利标题：Isolated isomers of norelgestromin and methods of making and using the same 专利权人：Richter Gedeon Vegyeszeti Gyar Rt.; The invention is directed to a process of preparing substantially pure d-(17?)-13-ethyl-17-hydroxy-1819-dinorpregn-4-ene-20-yn-3-one-3E- and -3Z-oxime isomers as well as a process for the synthesis of the mixture of isomers and the pure isomers. The invention also relates to substantially pure d-(17?)-13-ethyl-17-hydroxy-1819-dinorpregn-4-ene20-yn-3-one-3E-oxime and substantially pure d-(17?)-13-ethyl-17-hydroxy-1819-dinorpregn-4-ene-20-yn-3-one-3Z-oxime isomer. Further aspects of the invention ...

	2. US7576226B2	2009/8/18
	专利标题：Process of making isomers of norelgestromin and methods using the same 专利权人：Richter Gedeon Vegyeszeti Gyar Rt.; The invention is directed to a process of preparing substantially pure d-(17α)-13-ethyl-17-hydroxy-1819-dinorpregn-4-ene-20-yn-3-one-3E- and -3Z-oxime isomers as well as a process for the synthesis of the mixture of isomers and the pure isomers. The invention also relates to substantially pure d-(17α)-13-ethyl-17-hydroxy-1819-dinorpregn-4-ene20-yn-3-one-3E-oxime and substantially pure d-(17α)-13-ethyl-17-hydroxy-1819-dinorpregn-4-ene-20-yn-3-one-3Z-oxime isomer. Further aspects...

	3. EP2086522A2	2009/8/12
	专利标题：Transdermal therapeutic system comprising norelgestromin for contraception and hormone replacement 专利权人：Lts Lohmann Therapie-systeme Ag;

	4. DE102006050558B4	2009/3/26
	专利标题：Transdermales therapeutisches system enthaltend norelgestromin zur kontrazeption und hormonsubstitution 专利权人：Lts Lohmann Therapie-systeme Ag; Transdermal patch for administering norelgestromin comprises a drug-impermeable backing layer and a matrix layer comprising norelgestromin a silicone and diethylene glycol monoethyl ether butanediol or propylene glycol. - ACTIVITY None given. - MECHANISM OF ACTION Progestin.

	5. US20080279915A1	2008/11/13
	专利标题：Matrix-controlled transdermal therapeutic system based on an adhesive for administering norelgestromin or the combination thereof with an estrogen 专利权人：HEXAL AG; The invention relates to a transdermal therapeutic system comprising an active-ingredient-impermeable top layer an active-ingredient-containing matrix and a removable protective layer the matrix comprising or consisting of norelgestromin and an optional oestrogen as active ingredients as well as also a pressure-sensitive hot-melt adhesive and optional auxiliaries.

	6. US7393964B2	2008/7/1
	专利标题：Process for the preparation of norelgestromin 专利权人：Sterling Srl; Process for the preparation of Norelgestromin or 17α-hydroxy-13β-ethyl-1819-dinorpregn-4-ene-20-yn-3-one oxime also in crystalline form in particular with an E/Z isomer ratio of between 1.3 and 1.5.

	7. WO2008049516A3	2008/6/19
	专利标题：Transdermal therapeutic system comprising norelgestromin for contraception and hormone replacement 专利权人：Lts Lohmann Therapie-systeme Ag; The present invention relates to a transdermal therapeutic system for applying the active ingredient norelgestromin onto the skin optionally in combination with estrogens. It further relates to the use of such systems for hormonal contraception and for hormone replacement therapy.

	8. WO2008049516A2	2008/5/2
	专利标题：Transdermal therapeutic system comprising norelgestromin for contraception and hormone replacement 专利权人：Lts Lohmann Therapie-systeme Ag; The present invention relates to a transdermal therapeutic system for applying the active ingredient norelgestromin onto the skin optionally in combination with estrogens. It further relates to the use of such systems for hormonal contraception and for hormone replacement therapy.

	9. CA2645823A1	2008/5/2
	专利标题：Transdermal therapeutic system comprising norelgestromin forcontraception and hormone replacement 专利权人：Lts Lohmann Therapie-systeme Ag;

	10. DE102006050558A1	2008/4/30
	专利标题：Transdermal patch for administering norelgestromin has a matrix layer comprising norelgestromin, a silicone and diethylene glycol monoethyl ether, butanediol or propylene glycol 专利权人：Lts Lohmann Therapie-systeme Ag; Transdermal patch for administering norelgestromin comprises a drug-impermeable backing layer and a matrix layer comprising norelgestromin a silicone and diethylene glycol monoethyl ether butanediol or propylene glycol. - ACTIVITY None given. - MECHANISM OF ACTION Progestin.

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