Schistosomicidal compositions containing a compound of the formula-lt;CHEMgt;wherein Rlt;1gt; and Rlt;2gt; each hydrogen C1-C4 alkyl hydroxy-C1-C4 alkyl or C3-C6 cycloalkyl;Rlt;3gt; is nitro cyano fluorine chlorine bromine or iodineand Rlt;4gt; is methyl or hydroxymethyl;or a pharmaceutically acceptable acid addition salt thereof;and a compound of the formula-lt;CHEMgt;wherein R is cyclohexyl 3-cyclohexenyl 4-pyridyl phenyl 2-fluorophenyl or 4-aminophenyl with or without a pharmaceutically accep...

Schistosomicidal compositions containing a compound of the formula:-wherein R1 and R2 each hydrogen C1-C4 alkyl hydroxy-Ci-C4 alkyl or C3-C6 cycloalkyl; R3 is nitro cyano fluorine chlorine bromine or iodine and R4 is methyl or hydroxymethyl; or a pharmaceutically acceptable acid addition salt thereof; and a compound of the formula:-wherein R is cyclohexyl 3-cyclohexenyl 4-pyridyl phenyl 2-fluorophenyl or 4-aminophenyl with or without a pharmaceutically acceptable diluent or carrier. Preferably c...