The present invention relates to novel therapeutic uses of niclosamide for the treatment of cancer. In particular a combination of niclosamide or one of its derivatives with an alkylating agent is provided for the treatment of solid tumors. Moreover niclosamide or one of its derivatives can be used for the treatment of solid tumors characterized by underexpression of NFKBIA. Finally the invention relates to diagnostic methods for determining whether treatment with niclosamide alone or in combina...

The present invention relates to novel therapeutic uses of niclosamide for the treatment of cancer. In particular a combination of niclosamide or one of its derivatives with an alkylating agent is provided for the treatment of solid tumors. Moreover niclosamide or one of its derivatives can be used for the treatment of solid tumors characterized by underexpression of NFKBIA. Finally the invention relates to diagnostic methods for determining whether treatment with niclosamide alone or in combina...

A composition dosage form and kit for reducing an HIV viral load in a subject infected with HIV. The composition and the dosage form comprises the following ingredients in mass percentages 40% praziquantel 33% niclosamide and 27% albendazole while the kit comprises separate dosage forms of the ingredients.

FIELD: medicine.SUBSTANCE: invention relates to veterinary and is intended for fighting carp bothriocephalosis in fish farms on water reservoirs coolers of thermal and nuclear power stations. Method of obtaining anti-helminth medication against fish bothriocephalosis is characterised by the following: niclosamide is introduced into propyleneglycol in ratio 3:1 solution is brought to boiling and mixed until niclosamide completely dissolves after which filling agent - zeolite tufa - is added in ra...

PURPOSE: A pharmaceutical composition containing a statin-based drug and Wnt signal transduction regulator is provided to suppress MMP-9 expression and to prevent or treat arteriosclerosis and stroke. CONSTITUTION: A pharmaceutical composition for preventing or treating arteriosclerosis and stroke contains a statin-based drug and Wnt signal transduction regulator as active ingredients. The statin-based drug is selected from the group consisting of simvastain atorvastatin pravastatin pitavastatin...