The present invention relates to a protective agent suitable to protect the human skin against toxic materials, particularly against chemicals with nucleophilic sites. The active moiety is a polyanhydride derivative. The active transdermal retardant offers a barrier property and chemically and/or physically reacts with harmful chemicals to decrease percutaneous absorption. In the preferred embodiments, polyanhydride in its low molecular weight form reduced flux of nicotine and nitrofurazone sign...

The present invention relates to a protective agent suitable to protect the human skin against toxic materials particularly against chemicals with nucleophilic sites. The active moiety is a polyanhydride derivative. The active transdermal retardant offers a barrier property and chemically and/or physically reacts with harmful chemicals to decrease percutaneous absorption. In the preferred embodiments polyanhydride in its low molecular weight form reduced flux of nicotine and nitrofurazone signif...

PURPOSE: Provided is a method for producing a therapeutic ointment for treatment of burns by using as an ointment base algin and xanthan gum. The ointment has high biocompatibility reduces incidence of secondary infection and is very efficient for the rapid and successful treatment of burns. CONSTITUTION: About 20g of algin is added to 200ml of sterilized distilled water and agitated together with 0.7g of nitrofurazone and 3.84g of glycerin using a mechanical agitator for 1hr. In experiments on ...