PURPOSE: An oral formulation containing lansoprazole is provided to improve an elution property at pH 5.5 without the loss of activity caused by gastric acid and to effectively transfer lansoprazole into body through oral administration. CONSTITUTION: An oral formulation containing lansoprazole as an active ingredient. The oral formulation comprises: a spherical core containing lansoprazole as an active ingredient and has a central value of 90-1000 micrometers; an intermediate layer which is for...

The present invention relates to stable pharmaceutical compositions of (R)-lansoprazole or pharmaceutically acceptable salts thereof and process of preparing the same. The invention particularly provides pharmaceutical compositions of optically active (R)-isomer of lansoprazole with at least two functional coating layers.

An acid-unstable insoluble lansoprazole-containing oral formulation and a method of preparing the same are provided. The lansoprazole-containing oral formulation is resistant to activity loss caused by gastric juice has improved dissolution characteristics and thus ensures effective delivery of lansoprazole into the body through oral administration.