A method for the treatment of at least one symptom of gastro-esophageal reflux disease (GERD) in a human suffering from GERD administers an oral pharmaceutical dosage form into a gastro-intestinal tract of a human suffering from GERD. The oral pharmaceutical dosage form contains an acid susceptible proton pump inhibitor or salt thereof (PPI) an H2 receptor antagonist or salt thereof (H2RA) a pharmaceutically acceptable carrier and optionally an antacid agent and/or alginate. The PPI is selected ...

PROBLEM TO BE SOLVED: To provide a pharmaceutical formulation orally administrable of one or a plurality of active pharmaceutical ingredients (API) for providing quick oral intake. SOLUTION: There are provided a pharmaceutical formulation containing one or a plurality of APIs suitable for oral intake and cacao powder a method for producing the formulation and use of the formulation for therapy. As the APIs eletriptan terbutaline sulfate triazolam maleic acid chlorophenylamine dextropropoxyphene...

Disclosed is an oral unit dose form suitable for three-times-per-day administration to a subject in need of ibuprofen treatment, comprising ibuprofen and famotidine in a weight ratio in the range 29:1 to 31:1, and also comprising a barrier layer disposed between the famotidine and the ibuprofen wherein the ibuprofen and the famotidine are formulated for immediate release.

The invention concerns the use of an H1- and/or H2-histamine receptor antagonist for the reduction of intracranial pressure (ICP) in particular for the prevention and treatment of elevated intracranial pressure and/or secondary ischaemia in particular caused by brain injury more in particular caused by traumatic (TBI) and non-traumatic brain injury.In particular the histamine antagonist is selected from the group of acrivastine alimemazine antazoline astemizole azatadine azelastine bromphenirami...

The present invention provides to methods and compositions that treat or prevent deleterious effects associated with alcohol consumption including alcohol-induced flush reaction and hangover. The methods and compositions include famotidine and optionally succinic acid. The present invention further demonstrates compositions that include famotidine are effective at treating symptoms associated with a flush reaction in subjects that are not significantly responsive to treatments with the H1 antago...