PURPOSE: A therapeutic composition for periodontal diseases is provided to enable topical administration to a periodontal lesion and to continuously treat periodontitis. CONSTITUTION: A therapeutic composition for topical administration contains 2-50wt% of antibiotics 2-50wt% of polyacrylic acid polymer 2-50wt% of soluble polymer 0.04-10wt% of antioxidative ingredient and remaining amount of an ointment base. The antibiotics include one or more selected among minocycline tetracycline doxycycline...

Disclosed is the use of a solution comprising levofloxacin or ofloxacin and a divalent or trivalent cation for the preparation of an aerosol for treating a pulmonary infection wherein the aerosol can achieve a maximum lung sputum concentration (Cmax) of at least 1200 mg/L and a lung sputum area under the curve (AUC) of at least 1500 h·mg/L wherein the solution comprises a divalent or trivalent cation concentration from about 50 mM to about 400 mM and a levofloxacin or ofloxacin concentration fro...