A crystalline form of epirubicin hydrochloride named herein as \\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\typeII\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\" crystalline epirubicin hydrochloride has excellent thermal stability.Type II crystalline epirubicin hydrochloride has a powder X-ray diffractionpattern having average values of diffraction angle (2¿) and relativeintensity P(%) as presented in the following table (I)."

Compounds represented by general formula (I), pharmaceutically acceptable salts and solvates thereof or solvates of pharmaceutically acceptable salts are disclosed. wherein R1, R2, R3, R4, W and formula (II) are defined as in the application.