Pro-drugs of all non-steroidal anti-inflammatories with free acid function derivatized with an ester group which have the general structural formula given below (I) where A is: aspirin diflunisal benorylate ibufenac diclofenac indomethacin sulindac ketorolac ibuprofen naproxen ketoprofen fenoprofen flurbiprofen mefenamic acid meclof enamic acid flufenamic acid niflumic acid and where in the ester group R can be a sugar (amongst which aldose or ketose pentose or esose selected from a group of D- ...

The invention relates to novel multicomponent crystals to the production thereof and to the use thereof for treating pain conditions in particular of unclear genesis by means of a simultaneous effect on pains which are caused by muscle tension or degenerative joint diseases as well as on pains that are based on inflammatory processes. The novel multicomponent crystals contain ([2-amino-6-(4-fluoro-benzylamino)-pyridin-3-yl]-carbamic acid ethyl ester (flupirtine) and 2-[2-[(26-dichlorphenyl)-amin...

The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.

Method for producing enteric microcapsules without coating, containing diclofenac or one of the salts thereof with satisfactory anti-inflammatory activity and low gastric aggressiveness

Methods and formulations are provided for treating migraine and other acute pain episodes using diclofenac, and formulations of diclofenac that provide both rapid and sustained relief from acute pain. Methods and formulations are also provided for treating symptoms that often accompany migraine and acute pain such as photophobia, phonophobia, nausea and vomiting.

Methods and formulations are provided for treating migraine and other acute pain episodes using diclofenac and formulations of diclofenac that provide both rapid and sustained relief from acute pain. Methods and formulations are also provided for treating symptoms that often accompany migraine and acute pain such as photophobia phonophobia nausea and vomiting.

An adhesive patch in which an adhesion layer containing diclofenac or a salt thereof is formed on a supporting body, wherein: the adhesion layer contains a thermoplastic elastomer, a liquid paraffin, diclofenac or a salt thereof, and a dissolving agent