The invention provides an extended release coated granule comprising a granule having a particle size ranging from 0.2 to 2 mm a friability lower than or equal to 1% and comprising metoprolol succinate as active ingredient in an amount ranging from 10 to 75% by weight of the granule and at least one binder selected from microcrystalline cellulose and methylcellulose coated with a film-former coating agent. It also provides a process for the preparation of said extended release coated granules as...

Abstract Oral preparation with controlled release A pharmaceutical pellet is provided, comprising a spherical core containing the active substance with a smooth surface and a coating on the core, which controls pH-independent release of the active substance. With a pellet of this kind, the release of the active substance may follow a profile with a lag-phase from 60 minutes to 840 minutes, where during the lag-phase a proportion of 5 wt. % or less of the active substance is released. Furthermore...

La presente invencion se refiere al uso de un beta bloqueante para la fabricacion de un medicamento para el tratamiento de los hemangiomas por ejemplo de un los hemangiomas infantiles. El beta bloqueante puede ser un beta bloqueante no selectivo por ejemplo propranolol. La presente invencion proporciona una alternativa a los compuestos conocidos por ej. corticoides interferon o vincristina que se usan generalmente para el tratamiento de los hemangiomas. Reivindicacion 4: El uso de acuerdo con la...

The invention relates to an improved process for preparing metoprolol and its salts.

The invention relates to an improved process for preparing metoprolol and its salts.

The present invention relates to extended release dosage forms of metoprolol or salts thereof comprising a water insoluble and non-swellable inert core and one or more pharmaceutically acceptable excipients. The invention also relates to processes for the preparation of an inert core and extended release dosage forms.

The present invention relates to extended release dosage forms of metoprolol or salts thereof comprising a water insoluble and non-swellable inert core and one or more pharmaceutically acceptable excipients. The invention also relates to processes for the preparation of an inert core and extended release dosage forms.

The present invention relates to controlled porous osmotic pump tablets of high permeable drugs and the preparation process thereof. The controlled porosity osmotic pump tablets do not need to be drilled by laser, but provides controlled porosity for drug release by adding a suitable quantity of pore-forming agents into the semipermeable membrane. In specific embodiments, the present invention relates to controlled porous osmotic pump tablets comprising venlafaxine or metoprolol or pharmaceutica...