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[药品] 包含 'Metoprolol '

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	公开号	公开日	申请号	申请日

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当前查询条件: [药品] 包含 'Metoprolol '

	查询范围	在当前结果中查询
!	专利类型	发明实用新型外观设计
!	公开号			CN1234
!	申请号			CN1234
!	专利标题		扩展	PHARMA
!	专利权人		扩展	pfizer
	发明人
!	申请日			yyyymmdd
!	公开日			yyyymmdd
	优先权号
!	摘要		扩展	PHARMA
	IPC			A01B

1. PT82020A	1986/3/1	PT19860082020	1986/2/12
专利标题：PROCESS FOR PRODUCING 4-(2-METHOXYETHYL)-PHENYLGLYCIDYL ETHER AND/OR METOPROLOL 专利权人：GIST BROCADES NV [NL];

2. FI860599A0	1986/2/10
专利标题：Foerfarande foer framstaellning av 4-(2-metoxietyl)-fenylglycidyleter och/eller metoprolol. 专利权人：Gist-brocades N.v.;

3. CA1198125A1	1985/12/17	CA19820417934	1982/12/16
专利标题：METHOD FOR THE PREPARATION OF METOPROLOL 专利权人：HAESELE AB; A process for the preparation of metoprolol or 1isopropylamino-3-(4-(2-methoxy)ethylphenoxy)-2-propanol wherein 3-(4-(2-methoxy)ethyl)phenoxy-1,2-propanediol is reacted with thionyl chloride in dichlormethane in the presence of triethylamine to form 4-(4-((2-methoxy-ethyl)phenoxy)methyl)-1,3,2-dioxathiolane-2-oxide < IMG > which is then reacted with isopropylamine in acetonitrile.

4. CN85102267A	1985/11/10	CN19851002267	1985/4/1
专利标题：NEW PROCESS FOR SYNTHESIZING METOPROLOL 专利权人：ZHENGZHOU UNIVERSITY;

5. HU186649B	1985/8/28	HU19820004069	1982/12/16
专利标题：PROCESS FOR PRODUCING 1-ISOPROPYL-AMINO-3-SQUARE BRACKET-4-BRACKET-2-2-METHOXY-ETHYL-BRACKET CLOSED-PHENOXY-SQUARE BRACKET CLOSED-2-PROPANOL /METOPROLOL/ 专利权人：ORION YHTYMAE OY;

6. CH639065A5	1983/10/31	CH19790003012	1979/3/30
专利标题：Process for the preparation of 1-isopropylamino-3-[4-(2-methoxy- ethyl)phenoxy]-2-propanol 专利权人：HAESSLE AB [SE]; The compound with the trivial name metoprolol is prepared in a 3-step reaction. In the first step by reaction of 4-hydroxy- omega -methoxy- acetophenone with epichlorohydrin in the presence of a catalytic amount of triethylamine at elevated temperature. In the second step by reaction of the resulting 1-chloro-3-[4-(methoxymethylcarbonyl)- phenoxy]-2-propanol with isopropylamine in a solvent at elevated temperature. In the third step by reduction of the resulting 1-isopropylamino-3-[4-(methoxymet...

7. FI824231A	1983/6/18
专利标题：Foerfarande foer framstaellning av metoprolol 专利权人：Orion-yhtymae Oy;

8. FI824231A0	1982/12/9
专利标题：Foerfarande foer framstaellning av metoprolol 专利权人：Orion-yhtymae Oy;

9. NO146466C	1982/10/6	NO19790003121	1979/9/28
专利标题：Fremgangsmaate for fremstilling av et terapeutisk aktivt propanolamin, metoprolol 专利权人：Haessle, Ab,;

10. FR2487338B1	1982/9/17
专利标题：Procede perfectionne de preparation du (methoxy-2 ethyl)-4 phenol 专利权人：Sanofi; L'INVENTION SE RAPPORTE A UN PROCEDE DE PREPARATION DE (METHOXY-2 ETHYL)-4 PHENOL DE FORMULE:(CF DESSIN DANS BOPI)CARACTERISE EN CE QUE L'ON FAIT REAGIR UN BROMURE D'ALKYLOXY-4 PHENYL AVEC DU MAGNESIUM PUIS LE BROMURE D'ALKYLOXY-4 PHENYLMAGNESIUM OBTENU AVEC UN DERIVE METHOXYACETIQUE POUR FORMER UN ETHER QUE L'ON SCINDE PAR UN ACIDE MINERAL OU ORGANIQUE POUR OBTENIR LE (METHOXY-2 ETHYL)-4 PHENOL.LE PRODUIT PREPARE SELON L'INVENTION EST UN PRODUIT DE DEPART POUR LA SYNTHESE DU METOPROLOL.

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