专利信息

首页上页 1 2 3 4 5 6 7 8 下页尾页共 231 条记录, 当前第3/24页。

专利标题：Method for the preparation of 1-aryl-1-alkyl-3-dialkylaminopropane compounds

专利权人：SIEGFRIED AG [CH];

The present invention refers to the preparation of 1-aryl-1-alkyl-2-alkyl-3-dialkylamino-propane compounds, such as tapentadol, using a diastereoselective Eschenmoser-Claisen or Ireland-Claisen rearrangement.

专利标题：Tapentadol hydrochloride paracetamol orally disintegrating tablet and preparation method thereof

专利标题：SUBSTITUTED N-PENTANAMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF

The present invention relates to a (2R, 3R)-3-(3-substituted phenyl)-2-methyl n-pentanamide compounds as shown in the formula I and the preparation method thereof, wherein, the substituents are as defined in the specification, the present invention further relates to a use of the above compounds for the preparation of tapentadol II or its pharmaceutically acceptable salt, and the intermediates involved in the preparation process.

专利标题：Tapentadol hydrochloride crystal form c, and preparation method and application thereof

专利标题：Tapentadol compositions for pain management

专利权人：Grjunental' Gmbkh;

FIELD: medicine pharmaceutics.SUBSTANCE: given invention refers to a sustained-release tapentadol composition also containing a second active agent wherein the above second active agent is specified in tramadol pregabalin gabapentyl or pharmaceutically acceptable salts thereof. The given composition may be used to prepare a therapeutic agent for pain management. Besides the present invention refers to a method of managing pain and conditions related to pain by administering the given composition...

专利标题：Titration of tapentadol

专利权人：GRUENENTHAL GMBH;

专利标题：Tapentadol for treating pain associated with trigeminal neuralgia

专利权人：GRUENENTHAL GMBH;

The invention relates to tapentadol for use in the treatment of pain associated with disorders of the trigeminal nerve in particular for use in the treatment of pain associated with trigeminal neuralgia.

专利标题：SEMISOLID AQUEOUS PHARMACEUTICAL COMPOSITION CONTAINING TAPENTADOL.

专利权人：GRUENENTHAL GMBH [DE];

The invention relates to a semisolid aqueous pharmaceutical composition containing tapentadol or a physiologically acceptable salt thereof.

专利标题：AQUEOUS PHARMACEUTICAL FORMULATION OF TAPENTADOL FOR ORAL ADMINISTRATION.

专利权人：GRUENENTHAL GMBH [DE];

The invention relates to an aqueous pharmaceutical composition containing tapentadol or a physiologically acceptable salt thereof and being adapted for oral administration. The composition has excellent storage stability without relying on the presence of high amounts of preservatives.

专利标题：Semisolid aqueous pharmaceutical composition containing tapentadol

专利权人：GRUENENTHAL CHEMIE;

The invention relates to a semisolid aqueous pharmaceutical composition containing tapentadol or a physiologically acceptable salt thereof.

当前查询条件: [药品] 包含 'Tapentadol'

	查询范围	在当前结果中查询
!	专利类型	发明实用新型外观设计
!	公开号			CN1234
!	申请号			CN1234
!	专利标题		扩展	PHARMA
!	专利权人		扩展	pfizer
	发明人
!	申请日			yyyymmdd
!	公开日			yyyymmdd
	优先权号
!	摘要		扩展	PHARMA
	IPC			A01B

1. EP2674414A1	2013/12/18	EP20120004544	2012/6/15
专利标题：Method for the preparation of 1-aryl-1-alkyl-3-dialkylaminopropane compounds 专利权人：SIEGFRIED AG [CH]; The present invention refers to the preparation of 1-aryl-1-alkyl-2-alkyl-3-dialkylamino-propane compounds, such as tapentadol, using a diastereoselective Eschenmoser-Claisen or Ireland-Claisen rearrangement.

2. CN103432107A	2013/12/11	CN20131362877	2013/8/20
专利标题：Tapentadol hydrochloride paracetamol orally disintegrating tablet and preparation method thereof 专利权人：ANHUI PIOM PHARMACEUTICAL CO LTD;

3. EP2671878A1	2013/12/11	EP20120742093	2012/1/31
专利标题：SUBSTITUTED N-PENTANAMIDE COMPOUNDS, PREPARATION METHODS AND USES THEREOF 专利权人：SHANGHAI INST MATERIA MEDICA CHINESE ACADEMY OF SCIENCES [CN];TOPHARMAN SHANGHAI CO LTD [CN]; The present invention relates to a (2R, 3R)-3-(3-substituted phenyl)-2-methyl n-pentanamide compounds as shown in the formula I and the preparation method thereof, wherein, the substituents are as defined in the specification, the present invention further relates to a use of the above compounds for the preparation of tapentadol II or its pharmaceutically acceptable salt, and the intermediates involved in the preparation process.

4. CN102924303B	2013/11/20
专利标题：Tapentadol hydrochloride crystal form c, and preparation method and application thereof 专利权人：Hefei Nova Medicine Chemistry Co., Ltd.;

5. RU2497512C2	2013/11/10
专利标题：Tapentadol compositions for pain management 专利权人：Grjunental' Gmbkh; FIELD: medicine pharmaceutics.SUBSTANCE: given invention refers to a sustained-release tapentadol composition also containing a second active agent wherein the above second active agent is specified in tramadol pregabalin gabapentyl or pharmaceutically acceptable salts thereof. The given composition may be used to prepare a therapeutic agent for pain management. Besides the present invention refers to a method of managing pain and conditions related to pain by administering the given composition...

6. CN101730530B	2013/10/23
专利标题：Titration of tapentadol 专利权人：GRUENENTHAL GMBH;

7. WO2012136351A8	2013/10/17
专利标题：Tapentadol for treating pain associated with trigeminal neuralgia 专利权人：GRUENENTHAL GMBH; The invention relates to tapentadol for use in the treatment of pain associated with disorders of the trigeminal nerve in particular for use in the treatment of pain associated with trigeminal neuralgia.

8. MX2013010100A	2013/10/1	MX20130010100	2013/9/3
专利标题：SEMISOLID AQUEOUS PHARMACEUTICAL COMPOSITION CONTAINING TAPENTADOL. 专利权人：GRUENENTHAL GMBH [DE]; The invention relates to a semisolid aqueous pharmaceutical composition containing tapentadol or a physiologically acceptable salt thereof.

9. MX2013010101A	2013/10/1	MX20130010101	2013/9/3
专利标题：AQUEOUS PHARMACEUTICAL FORMULATION OF TAPENTADOL FOR ORAL ADMINISTRATION. 专利权人：GRUENENTHAL GMBH [DE]; The invention relates to an aqueous pharmaceutical composition containing tapentadol or a physiologically acceptable salt thereof and being adapted for oral administration. The composition has excellent storage stability without relying on the presence of high amounts of preservatives.

10. AU2012224954A1	2013/9/19	AU20120224954	2012/3/2
专利标题：Semisolid aqueous pharmaceutical composition containing tapentadol 专利权人：GRUENENTHAL CHEMIE; The invention relates to a semisolid aqueous pharmaceutical composition containing tapentadol or a physiologically acceptable salt thereof.

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